Evidence map›Paper›PMID 31925548›Full record

ReviewCurrent hypertension reports2020

Effect of Garlic's Active Constituents in Inflammation, Obesity and Cardiovascular Disease.

Isabel Quesada, Matilde de Paola, Carolina Torres-Palazzolo, Alejandra Camargo, León Ferder, Walter Manucha, Claudia Castro

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
10.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
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  6. Article
  7. Review
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  10. Review
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  14. In Vitro Antimicrobial Effectiveness Tests Using Garlic (Antibiotics (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Nutrients · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Isabel QuesadaCONICET Institute of Medicine and Experimental Biology of Cuyo (IMBECU), Mendoza, Argentina.
Matilde de PaolaCONICET Institute of Medicine and Experimental Biology of Cuyo (IMBECU), Mendoza, Argentina.
Carolina Torres-PalazzoloCONICET Agricultural Biology Institute of Mendoza (IBAM), Mendoza, Argentina.
Alejandra CamargoCONICET Agricultural Biology Institute of Mendoza (IBAM), Mendoza, Argentina.
León FerderDepartment of Pediatrics, Nephrology Division, Miller School of Medicine, University of Miami, Miami, FL, USA.
Walter ManuchaCONICET Institute of Medicine and Experimental Biology of Cuyo (IMBECU), Mendoza, Argentina.
Claudia CastroCONICET Institute of Medicine and Experimental Biology of Cuyo (IMBECU), Mendoza, Argentina. ccastro@fcm.uncu.edu.ar.
Universidad Nacional de Cuyo · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewSeveral studies have attributed garlic's beneficial properties to its high content of organosulfur compounds (OSCs). Here, we summarized recent studies published and some own findings regarding OSCs and its effects on cardiovascular disease, inflammation, and obesity. RECENT FINDING: The analysis of the multiple actions produced by OSCs suggests that many of its bioactivities interfere against inflammation, oxidative stress, obesogenic effects, and mitochondrial dysfunction. Accumulating evidence from in vitro, animal, and human studies reinforce the notion that OSCs modify signaling pathways that trigger chronic diseases, and to highlight, actions over these pathways are related to the treatment of disorders addressed in this review. Garlic's bioactive OSCs behave like a nutraceutical panacea because they cover a broad spectrum of applications with promising impact for the prevention and treatment of prevalent chronic pathologies associated with low-grade inflammation.

Indexed as

Cardiovascular DiseasesGarlicHypertensionObesityPlant ExtractsAnimalsHumansInflammationPlant ExtractsAtherosclerosisGarlicMitochondria dysfunctionOrganosulfur compoundsOverweightOxidative stress

Identifiers

PMID31925548
OpenAlexW3000166039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.