ArticlePediatric nephrology (Berlin, Germany)2020
Changes of cardiac functions after hemodialysis session in pediatric patients with end-stage renal disease: conventional echocardiography and two-dimensional speckle tracking study.
Article in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 23 citations in OpenAlex.
- Dialysis-associated cardiovascular disease risk in children: mechanism and management.Pediatric nephrology (Berlin, Germany) · 2026Review
- The association between systolic and diastolic dysfunction and autonomic nervous system function in children receiving chronic hemodialysis.Pediatric nephrology (Berlin, Germany) · 2025Observational
- Left ventricular myocardial functions in pediatric patients with primary nephrotic syndrome: a comprehensive evaluation using conventional echocardiography, two-dimensional speckle tracking, and three-dimensional echocardiography.Italian journal of pediatrics · 2025Observational
- The value of bioimpedance analysis in the assessment of hydration and nutritional status in children on chronic peritoneal dialysis.Renal failure · 2024Article
- Changes in echocardiographic parameters after hemodialysis session in a North African pediatric population with end-stage renal disease and without known heart disease.La Tunisie medicale · 2024Article
- Standardizing Blood Pressure Measurements in Pediatric Hemodialysis: a Collaborative Journey.Current hypertension reports · 2023Review
- Echocardiogram screening in pediatric dialysis and transplantation.Pediatric nephrology (Berlin, Germany) · 2023Review
- Left ventricular strain and left atrial strain are impaired during hemodialysis in children.The international journal of cardiovascular imaging · 2021Article
- Nutritional Assessment and Management in Paediatric Chronic Kidney Disease.Journal of nutrition and metabolism · 2021Review
- Natural History of Clinical, Laboratory, and Echocardiographic Parameters of a Primary Hyperoxaluria Cohort on Long Term Hemodialysis.Frontiers in medicine · 2021Article
- Left Ventricular Myocardial Deformations in Hemodialysis Children by Speckle Tracking Echocardiography.Clinical Medicine Insights. Cardiology · 2020Article
- Changes in serum cardiac troponin I after seizures: A marker for persistent subtle left ventricular myocardial dysfunctions in children with epilepsy.Annals of pediatric cardiologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough acute effects of hemodialysis (HD) on cardiac functions in end-stage renal disease (ESRD) have been studied frequently in adults, limited data are available in pediatric age. Therefore, this work elucidates the acute impact of HD on cardiac functions using conventional echocardiography and two-dimensional (2D) speckle tracking in ESRD pediatric patients.
methodsBetween June 2018 and April 2019, 40 ESRD pediatric subjects on chronic HD were prospectively recruited. All patients were subjected to history taking and baseline laboratory tests. Anthropometric measures, heart rate, blood pressure, and bioimpedance were assessed before and after HD session. Moreover, conventional echocardiography including M.mode and Doppler parameters for valves, as well as left ventricle (LV) 2D speckle tracking were performed pre- and post-dialysis session.
resultsThe included patients mean age was 12.9 ± 2.9 years, and males were 24 (60%). Significant reductions in body weight and blood pressure were noted after sessions. Post-dialysis LV and left atrial diameters, as well as left atrium to aortic diameter ratio, were lower. Nevertheless, conventional echocardiography-derived LV ejection fraction (EF), and fractional shortening were not significantly changed. Doppler-derived E/A ratio of mitral and tricuspid valves were lower post-dialysis. Global longitudinal strain (GLS) for LV was significantly reduced after dialysis (- 20.31 ± 3.58%, - 17.17 ± 3.40% vs, P < 0.0001), and global circumferential strain (GCS) was lower post-dialysis in comparison to pre-dialysis (- 21.37 ± 6.46% vs - 17.74 ± 6.16%, P < 0.0001). The speckle tracking-derived EF was significantly lower post-dialysis (57.58 ± 6.94 vs 53.64 ± 10.72, P = 0.018). All myocardial segments longitudinal and circumferential strains decreased significantly after dialysis.
conclusionsPost-hemodialysis significant decline in left ventricular EF as well as global and segmental strains can be detected in ESRD pediatric patients using 2D speckle tracking, despite the nonsignificant changes in systolic functions derived from conventional echocardiography. This is considered additional evidence of HD deleterious effect on myocardial functions, particularly in the pediatric age.
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