Evidence map›Paper›PMID 31925470›Full record

ArticleNeuroradiology2020

Are hemodynamics of irregular small carotid-ophthalmic aneurysms different from those of regular ones and large aneurysms based on numerical simulation?

Hailin Wan, Lei Huang, Liang Ge, Yeqing Jiang, Gaohui Li, Xiaochang Leng, Xiaoyuan Feng, Jianping Xiang, Xiaolong Zhang

Abstract read
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In one paragraph

Article in Neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. The Effectiveness and Safety of Ropivacaine and Medium-Dose Dexmedetomidine in Cesarean Section.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hailin WanDepartment of Radiology, Huashan Hospital, Fudan University, No. 12 Middle Wulumuqi Road, Shanghai, 200040, China.
Lei HuangDepartment of Radiology, Huashan Hospital, Fudan University, No. 12 Middle Wulumuqi Road, Shanghai, 200040, China.
Liang GeDepartment of Radiology, Huashan Hospital, Fudan University, No. 12 Middle Wulumuqi Road, Shanghai, 200040, China.
Yeqing JiangDepartment of Radiology, Huashan Hospital, Fudan University, No. 12 Middle Wulumuqi Road, Shanghai, 200040, China.
Gaohui LiArteryFlow Technology Co., Ltd, 459 Qianmo Road, Hangzhou, 310051, China.
Xiaochang LengArteryFlow Technology Co., Ltd, 459 Qianmo Road, Hangzhou, 310051, China.
Xiaoyuan FengDepartment of Radiology, Huashan Hospital, Fudan University, No. 12 Middle Wulumuqi Road, Shanghai, 200040, China.
Jianping XiangArteryFlow Technology Co., Ltd, 459 Qianmo Road, Hangzhou, 310051, China.
Xiaolong ZhangDepartment of Radiology, Huashan Hospital, Fudan University, No. 12 Middle Wulumuqi Road, Shanghai, 200040, China. xiaolongzhang@fudan.edu.cn.
Fudan University · CNHuashan Hospital · CN

Funding

National Nature Science Foundation of China 81371308National Nature Science Foundation of China 81771242
6 · The paper itself

Abstract

purposeThe purpose of this study is to investigate whether hemodynamics of unruptured, irregular small intracranial aneurysms (SIAs) are different from those of regular ones and large intracranial aneurysms (LIAs) in ophthalmic artery segment of internal carotid artery (ICA).

methodsBetween April 2015 and June 2018, 106 carotid-ophthalmic artery aneurysms were retrospectively analyzed using 3D angiographic images and computational fluid dynamics (CFD). Three categories were stratified: regular SIAs, irregular SIAs and LIAs. Statistical comparisons of the differences in clinical, morphological and hemodynamic parameters among regular SIA, irregular SIA and LIA groups were performed by one-way analysis of variance (ANOVA) or Kruskal-Wallis Test.

resultsThe median maximal height of regular SIA, irregular SIA and LIA were 3.03 (interquartile range: 2.49-4.22) mm, 4.59 (interquartile range: 3.86-5.32) mm and 11.06 (interquartile range: 9.28-13.69) mm, all P < 0.05). Low shear-stress area percentage (LSA%) and oscillatory shear index (OSI) of irregular SIAs and LIAs were not significantly different (P = 0.72, P = 0.27 respectively), and were significantly higher than those of regular SIAs (all P < 0.01). Wall shear stress (WSS) and normalized wall shear stress (NWSS) of irregular SIAs were significantly higher than those of LIAs (P < 0.01, P < 0.01 respectively), but lower than those of regular SIAs (P < 0.01, P < 0.01 respectively).

conclusionsSpecial unruptured irregular SIAs share a similarity of hemodynamic characteristics with LIAs in high LSA% and high OSI, and are different from regular SIAs in hemodynamics.

Indexed as

Carotid ArteriesCerebral AngiographyOphthalmic ArteryComputer SimulationFemaleHemodynamicsHumansHydrodynamicsImaging, Three-DimensionalIntracranial AneurysmMaleMiddle AgedRetrospective StudiesHemodynamicsMorphologyRuptureSmall intracranial aneurysmsWall shear stress

Identifiers

PMID31925470
OpenAlexW2999354750

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.