Evidence map›Paper›PMID 31925460›Full record

ReviewPediatric radiology2020

Pediatric multiple sclerosis: from clinical basis to imaging spectrum and differential diagnosis.

Igor G Padilha, Ana P A Fonseca, Ana L M Pettengill, Diego C Fragoso, Felipe T Pacheco, Renato H Nunes, Antonio C M Maia, Antônio J da Rocha

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The State of the Art of Pediatric Multiple Sclerosis.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Igor G PadilhaDivision of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr. 112, Vila Buarque, São Paulo, SP, 01221-020, Brazil. Igorpadilha.8@gmail.com.ORCID 0000-0002-7639-0397
Ana P A FonsecaDivision of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr. 112, Vila Buarque, São Paulo, SP, 01221-020, Brazil.
Ana L M PettengillDivision of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr. 112, Vila Buarque, São Paulo, SP, 01221-020, Brazil.
Diego C FragosoDivision of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr. 112, Vila Buarque, São Paulo, SP, 01221-020, Brazil.
Felipe T PachecoDivision of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr. 112, Vila Buarque, São Paulo, SP, 01221-020, Brazil.
Renato H NunesDivision of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr. 112, Vila Buarque, São Paulo, SP, 01221-020, Brazil.
Antonio C M MaiaDivision of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr. 112, Vila Buarque, São Paulo, SP, 01221-020, Brazil.
Antônio J da RochaDivision of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr. 112, Vila Buarque, São Paulo, SP, 01221-020, Brazil.
Faculdade de Ciências Médicas da Santa Casa de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric multiple sclerosis (MS) deserves special attention because of its impact on cognitive function and development. Although knowledge regarding pediatric MS has rapidly increased, understanding the peculiarities of this population remains crucial for disease management. There is limited expertise about the efficacy and safety of current disease-modifying agents. Although pathophysiology is not entirely understood, some risk factors and immunological features have been described and are discussed herein. While the revised International Pediatric MS Study Group diagnostic criteria have improved the accuracy of diagnosis, the recently revised McDonald criteria also offer some new insights into the pediatric population. It is fundamental that radiologists have strong knowledge about the vast spectrum of demyelinating disorders that can occur in childhood to ensure appropriate diagnosis and provide early treatment.

Indexed as

Age of OnsetChildDiagnosis, DifferentialHumansMultiple SclerosisBrainCentral nervous systemChildrenDemyelinationDiagnostic criteriaDifferential diagnosisMagnetic resonance imagingMultiple sclerosisSpinal cord

Identifiers

PMID31925460
OpenAlexW2999556997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.