ArticleNature communications2020
Plant metabolism of nematode pheromones mediates plant-nematode interactions.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 91 citations in OpenAlex.
- Overexpression ofPlant signaling & behavior · 2026Article
- Redox Regulation of Plant-Root-Knot Nematode Interactions: From ROS-Mediated Immunity to Sustainable Resistance.Antioxidants (Basel, Switzerland) · 2026Review
- The conserved nematode pheromone ascr#18 primes plant immunity.Communications biology · 2026Article
- Cyclohexyl acetate functions like a volatile sex pheromone mimic in Caenorhabditis nematodes.BMC biology · 2026Article
- Harnessing entomopathogenic nematodes for sustainable pest management: mechanisms, challenges, and innovations.Frontiers in plant science · 2026Review
- Nematode Pheromones as Key Mediators of Behavior, Development, and Ecological Interactions.Biomolecules · 2025Review
- Quorum Signaling Molecules: Interactions Between Plants and Associated Pathogens.International journal of molecular sciences · 2025Review
- Distribution of Trichostrongylus colubriformis on common pasture grasses and legumes from the Midwestern United States.PloS one · 2025Article
- Biotic interactions, evolutionary forces and the pan-plant specialized metabolism.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Meloidogyne incognita genes involved in the repellent behavior in response to ascr#9.Scientific reports · 2024Article
- A receptor for dual ligands governs plant immunity and hormone response and is targeted by a nematode effector.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Biochemical Defence of Plants against Parasitic Nematodes.Plants (Basel, Switzerland) · 2024Review
- Ascarosides and Symbiotic Bacteria of Entomopathogenic Nematodes Regulate Host Immune Response inInsects · 2024Article
- The fate of enterohemorrhagicFood bioscience · 2024Article
- Mitogen-activated protein kinases MPK3 and MPK6 phosphorylate receptor-like cytoplasmic kinase CDL1 to regulate soybean basal immunity.The Plant cell · 2024Article
- Secondary metabolites related to the resistance ofHeliyon · 2023Article
- Nematode Pheromones: Structures and Functions.Molecules (Basel, Switzerland) · 2023Review
- Recent Advances in Life History Transition with Nematode-Trapping FungusPathogens (Basel, Switzerland) · 2023Review
- Multiple Receptors Contribute to the Attractive Response of Caenorhabditis elegans to Pathogenic Bacteria.Microbiology spectrum · 2023Article
- Formation and function of dauer ascarosides in the nematodes Caenorhabditis briggsae and Caenorhabditis elegans.G3 (Bethesda, Md.) · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Microorganisms and nematodes in the rhizosphere profoundly impact plant health, and small-molecule signaling is presumed to play a central role in plant rhizosphere interactions. However, the nature of the signals and underlying mechanisms are poorly understood. Here we show that the ascaroside ascr#18, a pheromone secreted by plant-parasitic nematodes, is metabolized by plants to generate chemical signals that repel nematodes and reduce infection. Comparative metabolomics of plant tissues and excretions revealed that ascr#18 is converted into shorter side-chained ascarosides that confer repellency. An Arabidopsis mutant defective in two peroxisomal acyl-CoA oxidases does not metabolize ascr#18 and does not repel nematodes, indicating that plants, like nematodes, employ conserved peroxisomal β-oxidation to edit ascarosides and change their message. Our results suggest that plant-editing of nematode pheromones serves as a defense mechanism that acts in parallel to conventional pattern-triggered immunity, demonstrating that plants may actively manipulate chemical signaling of soil organisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.