ArticleNature communications2020
Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Multiplex detection of biogenic amines with SERS sensor array boosted by (metallo)porphyrin-based hydrogen-bonded organic frameworks.Analytical and bioanalytical chemistry · 2026Article
- Next-Generation SERS Probes: Engineering Hotspots, Intelligent Molecular Targeting, and AI-Driven Spectral Analysis for Emerging Applications.Nanomaterials (Basel, Switzerland) · 2026Review
- Label-Free SERS Fingerprinting of Neuroprotein Conformational Dynamics in Human Saliva.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- High-sensitivity SERS nanosensor for precise in situ tracking of caspase-1 during pyroptosis in macrophages.Mikrochimica acta · 2026Article
- The optical nose: Monolayer sensitization of Au surfaces for plasmonic gas sensing.Science advances · 2026Article
- Cellulose-based sensors for decentralized monitoring in precision agriculture.Nature communications · 2026Review
- Review
- Designing Physical Unclonable Functions From Optically Active Materials.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Nanomaterial-Enhanced Biosensing: Mechanisms and Emerging Applications.Advanced healthcare materials · 2025Review
- Open Raman Microscopy (ORM): A Modular Hardware and Software Framework for Accessible Raman Imaging.bioRxiv : the preprint server for biology · 2025Article
- SERS nose arrays based on a signal differentiation approach for TNT gas detection.Communications chemistry · 2025Article
- Plasmonic Molecular Entrapment for Label-Free Methylated DNA Detection and Machine-Learning Assisted Quantification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Advances in MEMS, Optical MEMS, and Nanophotonics Technologies for Volatile Organic Compound Detection and Applications.Small science · 2025Review
- Surface-Enhanced Raman Spectroscopy for Biomedical Applications: Recent Advances and Future Challenges.ACS applied materials & interfaces · 2025Review
- Gypsum heterogenous nucleation pathways regulated by surface functional groups and hydrophobicity.Nature communications · 2025Article
- Paper/GO/e-Au flexible SERS sensors forNanoscale advances · 2024Article
- Gold-copper oxide core-shell plasmonic nanoparticles: the effect of pH on shell stability and mechanistic insights into shell formation.Nanoscale advances · 2024Article
- Food for Thought: Optical Sensor Arrays and Machine Learning for the Food and Beverage Industry.ACS sensors · 2024Review
- Detection and Identification of Pesticides in Fruits Coupling to an Au-Au Nanorod Array SERS Substrate and RF-1D-CNN Model Analysis.Nanomaterials (Basel, Switzerland) · 2024Article
- Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Label-free surface-enhanced Raman spectroscopy (SERS) can interrogate systems by directly fingerprinting their components' unique physicochemical properties. In complex biological systems however, this can yield highly overlapping spectra that hinder sample identification. Here, we present an artificial-nose inspired SERS fingerprinting approach where spectral data is obtained as a function of sensor surface chemical functionality. Supported by molecular dynamics modeling, we show that mildly selective self-assembled monolayers can influence the strength and configuration in which analytes interact with plasmonic surfaces, diversifying the resulting SERS fingerprints. Since each sensor generates a modulated signature, the implicit value of increasing the dimensionality of datasets is shown using cell lysates for all possible combinations of up to 9 fingerprints. Reliable improvements in mean discriminatory accuracy towards 100% are achieved with each additional surface functionality. This arrayed label-free platform illustrates the wide-ranging potential of high-dimensionality artificial-nose based sensing systems for more reliable assessment of complex biological matrices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.