Evidence map›Paper›PMID 31924743›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Metabolic dysregulation in the

Clavia Ruth Wooton-Kee, Matthew Robertson, Ying Zhou, Bingning Dong, Zhen Sun, Kang Ho Kim, Hailan Liu, Yong Xu, Nagireddy Putluri, Pradip Saha and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 56 citations in OpenAlex.

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  4. Role of cuproptosis in digestive system tumors (Review).International journal of molecular medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Clavia Ruth Wooton-KeeDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; wootenke@bcm.edu moore@bcm.edu antar@bcm.edu.
Matthew RobertsonDan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030.
Ying ZhouDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030.
Bingning DongDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030.
Zhen SunDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030.
Kang Ho KimDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030.
Hailan LiuDepartment of Pediatrics, Baylor College of Medicine, Houston, TX 77030.
Yong XuDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030.
Nagireddy PutluriDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030.
Pradip SahaDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030.
Cristian CoarfaDan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030.
David D MooreDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; wootenke@bcm.edu moore@bcm.edu antar@bcm.edu.ORCID 0000-0002-5151-9748
Alli M Nuotio-AntarDepartment of Pediatrics, Baylor College of Medicine, Houston, TX 77030 wootenke@bcm.edu moore@bcm.edu antar@bcm.edu.ORCID 0000-0002-1830-4868
Baylor College of Medicine · US

Funding

UM1HG006348: Cas9 Genome Integrity Supplemental ProposalUM1HG006348 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI Jason D. Heaney, Chih-Wei Logan Hsu · 2016 to 2026
$47.5M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
METABOLIC IMPACTS OF TYPE II INTERFERON SIGNALS IN OBESITYR01DK114356 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI HARTIG, SEAN · 2017 to 2025
$4.6M
Nuclear Receptors as Novel Therapeutic Targets for Wilson’s DiseaseK01DK111716 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI WOOTON-KEE, CLAVIA RUTH · 2017 to 2021
$746k
NHGRI NIH HHS UM1 HG006348NIDDK NIH HHS K01 DK111716NIDDK NIH HHS P30 DK056338NIDDK NIH HHS R01 DK114356
6 · The paper itself

Abstract

Inactivating mutations in the copper transporter

Indexed as

AnimalsCopper-Transporting ATPasesDisease Models, AnimalFemaleGlucoseHepatolenticular DegenerationHumansInsulin ResistanceLiverMaleMetabolomeMiceMice, Inbred C57BLMice, KnockoutAtp7b protein, mouseCopper-Transporting ATPasesGlucosecopperlivernuclear receptors

Identifiers

PMID31924743
PMCPMC6994990
OpenAlexW2999098670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.