Evidence map›Paper›PMID 31924717›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Positron Lymphography via Intracervical

Jennifer J Mueller, Lawrence T Dauer, Rajmohan Murali, Alexia Iasonos, Neeta Pandit-Taskar, Nadeem R Abu-Rustum, Jan Grimm

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Molecular image-guided surgery in gynaecological cancer: where do we stand?European journal of nuclear medicine and molecular imaging · 2024
    Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jennifer J MuellerGynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Lawrence T DauerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Rajmohan MuraliDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Alexia IasonosDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Neeta Pandit-TaskarMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Nadeem R Abu-RustumGynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Jan GrimmMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York grimmj@mskcc.org.
Memorial Sloan Kettering Cancer Center · USCornell University · USWeill Cornell Medicine · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The presence of metastasis in local lymph nodes (LNs) is a key factor influencing choice of therapy and prognosis in cervical and endometrial cancers; therefore, the exploration of sentinel LNs (SLNs) is highly important. Currently, however, SLN mapping requires LN biopsy for pathologic evaluation, since there are no clinical imaging approaches that can identify tumor-positive LNs in early stages. Staging lymphadenectomy poses risks, such as leg lymphedema or lymphocyst formation. Furthermore, in 80%-90% of patients, the explored LNs are ultimately tumor-free, meaning most patients are unnecessarily subjected to lymphadenectomy.

Indexed as

Cervix UteriLymphographyPreoperative PeriodAdultAgedAged, 80 and overEndometrial NeoplasmsFalse Positive ReactionsFemaleFluorodeoxyglucose F18HumansImaging, Three-DimensionalInjectionsMiddle AgedPositron Emission Tomography Computed TomographySentinel Lymph Node BiopsyFluorodeoxyglucose F18cervical cancermetastasisPETpositron lymphographysentinel lymph node

Identifiers

PMID31924717
PMCPMC7413230
OpenAlexW3000601522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.