Evidence map›Paper›PMID 31924657›Full record

ArticleGut2020

The study of Lynch syndrome in a special population reveals a strong founder effect and an unusual mutational mechanism in familial adenomatous polyposis.

Abdul K Siraj, Tariq Masoodi, Rong Bu, Sandeep Kumar Parvathareddy, Sarah Siraj, Ali Alassiri, Fouad Al-Dayel, Fowzan S Alkuraya, Khawla S Al-Kuraya

Open access · hybridAbstract readLetterComment
In one paragraph

Article in Gut, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Genotype-phenotype correlations inOncology reviews · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Abdul K Siraj *Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Tariq Masoodi *Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Rong Bu *Human Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Sandeep Kumar ParvathareddyHuman Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Sarah SirajHuman Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Ali AlassiriDepartment of Pediatric Surgery, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Fouad Al-DayelDepartment of Pathology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Fowzan S AlkurayaDepartment of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Khawla S Al-KurayaHuman Cancer Genomic Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia kkuraya@kfshrc.edu.sa.ORCID 0000-0002-8430-6693
King Faisal Specialist Hospital & Research Centre · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenomatous Polyposis ColiColorectal Neoplasms, Hereditary NonpolyposisFounder EffectHumansMutationProspective Studiescolorectal cancerfamilial adenomatous polyposisHNPCC syndrome

Identifiers

PMID31924657
PMCPMC7569390
OpenAlexW2999886329

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.