ReviewCell2020
Neural Control and Modulation of Thirst, Sodium Appetite, and Hunger.
Review in Cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it, 138 citations in OpenAlex.
- Effects of Non-Pharmacological Interventions on Degree of Thirst and Oral Mucosal Moisture in Critically Ill Patients: A Systematic Review and Meta-Analysis.Nursing in critical care · 2026Pooled it
- A randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia.The Journal of clinical investigation · 2021Trial
- Validity of different copeptin assays in the differential diagnosis of the polyuria-polydipsia syndrome.Scientific reports · 2021Trial
- Cell-type-resolved RNA-seq reveals molecular signatures of sexual experience inNAR genomics and bioinformatics · 2026Article
- The critical role of gut-brain signalling in eating behaviour and obesity.Nature reviews. Gastroenterology & hepatology · 2026Review
- Disparity in the regulation and prevention of water versus sodium imbalance in heat-stress nephropathy: a phylogenetic perspective.Clinical kidney journal · 2026Review
- A neuron-glia circuit anticipates hypoxia to regulate organismal oxygen use.bioRxiv : the preprint server for biology · 2026Article
- Tumor-induced orexigenic imbalance lowers protein appetite and drives early organ wasting symptoms.Nature communications · 2026Article
- Accumulation of prosaposin and progranulin around the subfornical organ induces polydipsia in SAP-D-deficient mice.Biochemistry and biophysics reports · 2026Article
- Thirst in End-Stage Liver Disease: From Symptom Disregard to a Multidisciplinary Clinical Pathway and Future Perspectives: A Narrative Review.Journal of multidisciplinary healthcare · 2026Review
- An automated two-choice social operant task for probing moment-to-moment changes in social satiety.iScience · 2025Article
- Insular cortex predictions regulate glucose homeostasis.bioRxiv : the preprint server for biology · 2025Article
- A bottom-up septal inhibitory circuit mediates anticipatory control of drinking.Nature neuroscience · 2025Article
- Molecular and functional diversity of the autonomic nervous system.Nature reviews. Neuroscience · 2025Review
- Article
- Flexible value coding in the mesolimbic dopamine system depending on internal water and sodium balance.NPJ science of food · 2025Article
- Targeted cravings: Unraveling the drivers of nutrient-specific appetite.Current opinion in neurobiology · 2025Review
- Distinct neural representations of hunger and thirst in neonatal mice before the emergence of food- and water-seeking behaviors.Current biology : CB · 2025Article
- Body fluid regulation.Current opinion in neurobiology · 2025Review
- Pathogen infection induces sickness behaviors through neuromodulators linked to stress and satiety in C. elegans.Nature communications · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The function of central appetite neurons is instructing animals to ingest specific nutrient factors that the body needs. Emerging evidence suggests that individual appetite circuits for major nutrients-water, sodium, and food-operate on unique driving and quenching mechanisms. This review focuses on two aspects of appetite regulation. First, we describe the temporal relationship between appetite neuron activity and consumption behaviors. Second, we summarize ingestion-related satiation signals that differentially quench individual appetite circuits. We further discuss how distinct appetite and satiation systems for each factor may contribute to nutrient homeostasis from the functional and evolutional perspectives.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.