Evidence map›Paper›PMID 31923179›Full record

ArticlePloS one2020

Comparison of post-transplantation diabetes mellitus incidence and risk factors between kidney and liver transplantation patients.

Vidit N Munshi, Soroush Saghafian, Curtiss B Cook, K Tuesday Werner, Harini A Chakkera

Open access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Novel Pharmacy Model: Pharmacy Diabetes Clinic in Abdominal Transplant Recipients.Diabetes spectrum : a publication of the American Diabetes Association · 2024
    Article
  4. Review
  5. Article
  6. Posttransplantation Diabetes Mellitus Among Solid Organ Recipients in a Danish Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Article
  7. Article
  8. Management of post-transplant diabetes: immunosuppression, early prevention, and novel antidiabetics.Transplant international : official journal of the European Society for Organ Transplantation · 2021
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Vidit N MunshiPhD Program in Health Policy, Harvard University, Cambridge, Massachusetts, United States of America.ORCID 0000-0003-0290-5148
Soroush SaghafianHarvard Kennedy School, Harvard University, Cambridge, Massachusetts, United States of America.
Curtiss B CookMayo Clinic Arizona, Scottsdale, Arizona, United States of America.
K Tuesday WernerMayo Clinic Arizona, Scottsdale, Arizona, United States of America.
Harini A ChakkeraMayo Clinic Arizona, Scottsdale, Arizona, United States of America.
Mayo Clinic in Arizona · USHarvard University · USHarvard University Press · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost prior studies characterizing post-transplantation diabetes mellitus (PTDM) have been limited to single-cohort, single-organ studies. This retrospective study determined PTDM across organs by comparing incidence and risk factors among 346 liver and 407 kidney transplant recipients from a single center.

methodsUnivariate and multivariate regression-based analyses were conducted to determine association of various risk factors and PTDM in the two cohorts, as well as differences in glucometrics and insulin use across time points.

resultsThere was a higher incidence of PTDM among liver versus kidney transplant recipients (30% vs. 19%) at 1-year post-transplant. Liver transplant recipients demonstrated a 337% higher odds association to PTDM (OR 3.37, 95% CI (1.38-8.25), p<0.01). 1-month FBG was higher in kidney patients (135 mg/dL vs 104 mg/dL; p < .01), while 1-month insulin use was higher in liver patients (61% vs 27%, p < .01). Age, BMI, insulin use, and inpatient FBG were also significantly associated with differential PTDM risk.

conclusionsKidney and liver transplant patients have different PTDM risk profiles, both in terms of absolute PTDM risk as well as time course of risk. Management of this population should better reflect risk heterogeneity to short-term need for insulin therapy and potentially long-term outcomes.

Indexed as

Diabetes MellitusFemaleHumansImmunosuppression TherapyIncidenceInsulinKidney TransplantationLiver TransplantationMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsInsulin

Identifiers

PMID31923179
PMCPMC6953760
OpenAlexW3000639639

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.