Evidence map›Paper›PMID 31922103›Full record

ArticleIndian journal of sexually transmitted diseases and AIDS

Persons living with HIV continue to present late for care: A trend analysis from 2011 to 2015.

Abhijit Vasantrao Kadam, Shilpa Chandrashekhar Bembalkar, Narayan Uddhavrao Panchal, Megha Sunil Mamulwar, Ashwini Vinod Shete, Sheela Virendra Godbole

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Article in Indian journal of sexually transmitted diseases and AIDS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Abhijit Vasantrao KadamDepartment of Clinical Sciences, ICMR National AIDS Research Institute, Bhosari, Pune, Maharashtra, India.
Shilpa Chandrashekhar BembalkarDepartment of Epidemiology and Biostatistics, ICMR National AIDS Research Institute, Bhosari, Pune, Maharashtra, India.
Narayan Uddhavrao PanchalDepartment of Clinical Sciences, ICMR National AIDS Research Institute, Bhosari, Pune, Maharashtra, India.
Megha Sunil MamulwarDepartment of Epidemiology and Biostatistics, ICMR National AIDS Research Institute, Bhosari, Pune, Maharashtra, India.
Ashwini Vinod SheteDepartment of Immunology and Serology, ICMR National AIDS Research Institute, Bhosari, Pune, Maharashtra, India.
Sheela Virendra GodboleDepartment of Epidemiology and Biostatistics, ICMR National AIDS Research Institute, Bhosari, Pune, Maharashtra, India.
National AIDS Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThe clinical and prevention benefits of early initiation of antiretroviral therapy (ART) have led to the adoption of test and treat policy for HIV. Early diagnosis of HIV is crucial for maximal benefits from ART.

aimsThis study aims to assess trends in CD4 cell counts at diagnosis and determinants of late presentation. SETTINGS AND

designWe analyzed 5-year data from a free HIV/sexually transmitted infection referral clinic immune. SUBJECTS AND

methodsPersons presenting for HIV testing from January 2011 to December 2015, for whom CD4 cell count results were available within 3 months of HIV diagnosis, were included in the analysis. Persons on ART were excluded from the study. STATISTICAL ANALYSIS: The predictors of CD4 cell count at presentation were assessed using univariate and multivariate linear regression.

resultsOf 1001 persons diagnosed HIV-1 positive, 659 had received CD4 test within 3 months of diagnosis. The median CD4 count at presentation ranged from 212 to 352 cells/cmm in these 5 years and did not show any significant change with time. Nearly 40% had CD4 cell counts below 200 cells/cmm (AIDS); additionally, 23% presented below 350 cells/cmm. Older age (beta: -5.78;

conclusionBetween 2011 and 2015, persons with HIV continued to present late in spite of changes in ART access program. Education focused on the benefits of early diagnosis and availability of free immediate treatment in the public sector, are crucial to the achievement of the India's 90-90-90 goals.

Indexed as

CD4 cell count at presentationHIV diagnosistrends

Identifiers

PMID31922103
PMCPMC6896389
OpenAlexW2990238620

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LicenceCC BY-NC-SA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.