Evidence map›Paper›PMID 31922084›Full record

ArticleCurrent developments in nutrition2020

Effect of a Family-Based Intervention on Nutrient Biomarkers, Desaturase Enzyme Activities, and Cardiometabolic Risk Factors in Children with Overweight and Obesity.

Nirupa R Matthan, Judith Wylie-Rosett, Xiaonan Xue, Qi Gao, Adriana E Groisman-Perelstein, Pamela M Diamantis, Mindy Ginsberg, Yasmin Mossavar-Rahmani, Kathryn Barger, Alice H Lichtenstein

Open access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Pediatric obesity: prevention is better than care.Italian journal of pediatrics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nirupa R MatthanCardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA.
Judith Wylie-RosettDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Xiaonan XueDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Qi GaoDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Adriana E Groisman-PerelsteinDepartment of Pediatrics, Albert Einstein College of Medicine, Jacobi Medical Center, Bronx, NY, USA.
Pamela M DiamantisDepartment of Pediatrics, Albert Einstein College of Medicine, Jacobi Medical Center, Bronx, NY, USA.
Mindy GinsbergDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Yasmin Mossavar-RahmaniDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Kathryn BargerBiostatistics and Data Management Core Unit, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA.
Alice H LichtensteinCardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA.ORCID 0000-0002-1053-9478
Albert Einstein College of Medicine · USTufts University · US

Funding

Stable Isotope and Metabolomics CoreP60DK020541 · NIDDK · YESHIVA UNIVERSITY · PI PESSIN, JEFFREY E. · 1986 to 2014
$29.8M
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY E. PESSIN · 2015 to 2026
$27.7M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Comprehensive Approach to Family Weight ManagementR18DK075981 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI WYLIE-ROSETT, JUDITH · 2008 to 2012
$3.7M
Diet Quality and CVD Risk Factors in a Family Based Weight Management StudyR01HL101236 · NHLBI · TUFTS UNIVERSITY BOSTON · PI LICHTENSTEIN, ALICE H · 2010 to 2013
$1.4M
NHLBI NIH HHS R01 HL101236NIDDK NIH HHS P30 DK020541NIDDK NIH HHS P30 DK111022NIDDK NIH HHS P60 DK020541NIDDK NIH HHS R18 DK075981
6 · The paper itself

Abstract

backgroundDeveloping dietary strategies to prevent excess weight gain during childhood is critical to stem the current obesity epidemic and associated adverse cardiometabolic consequences.

objectivesWe aimed to assess how participation in a family-based weight-management intervention affected nutrient biomarkers and cardiometabolic risk factors (CMRFs) in children (7-12 y old;

methodsThis was a secondary analysis from a randomized-controlled, parallel-arm clinical trial. Families of children, recruited from a largely Hispanic population, were assigned to Standard Care (SC; American Academy of Pediatrics overweight/obesity recommendations), or SC + Enhanced Program (SC + EP; 8 skill-building cores, monthly support sessions, targeted diet/physical activity strategies). Nutrient biomarkers (plasma carotenoids, fat-soluble vitamins, RBC fatty acid profiles, desaturase indexes) and CMRFs were measured in archived blood samples collected at baseline and the end of the 1-y intervention.

resultsChildren in both groups had significantly lower

conclusionsProviding targeted family-based behavioral counseling, as part of SC, can help overweight/obese children adopt healthier eating patterns that are associated with modest improvements in BMI

Indexed as

adipokinescardiometabolic risk factorscarotenoidschildhood obesityfamily-based interventionfatty acidsnutrient biomarkers

Identifiers

PMID31922084
PMCPMC6943838
OpenAlexW2993965352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.