Evidence map›Paper›PMID 31922059›Full record

ArticleKidney international reports2020

Safety, Feasibility, and Efficacy of Early Rehabilitation in Patients Requiring Continuous Renal Replacement: A Quality Improvement Study.

Kirby P Mayer, Amanda R Hornsby, Victor Ortiz Soriano, Timothy C Lin, Jennifer T Cunningham, Hanwen Yuan, Caroline E Hauschild, Peter E Morris, Javier A Neyra

Abstract read
In one paragraph

Article in Kidney international reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Intensive Care Unit-Acquired Weakness in Patients With Acute Kidney Injury: A Contemporary Review.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kirby P MayerDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, USA.
Amanda R HornsbyInpatient Rehabilitation Department, Chandler Medical Center, University of Kentucky, Lexington, Kentucky, USA.
Victor Ortiz SorianoDepartment of Internal Medicine, Division of Nephrology, Bone and Mineral Metabolism, University of Kentucky, Lexington, Kentucky, USA.
Timothy C LinInpatient Rehabilitation Department, Chandler Medical Center, University of Kentucky, Lexington, Kentucky, USA.
Jennifer T CunninghamInpatient Rehabilitation Department, Chandler Medical Center, University of Kentucky, Lexington, Kentucky, USA.
Hanwen YuanData, Analytics, and Statistical Core (DASC), Center for Health Services Research, University of Kentucky, Lexington, Kentucky, USA.
Caroline E HauschildDepartment of Internal Medicine, Division of Nephrology, Bone and Mineral Metabolism, University of Kentucky, Lexington, Kentucky, USA.
Peter E MorrisDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Kentucky, Lexington, Kentucky, USA.
Javier A NeyraDepartment of Internal Medicine, Division of Nephrology, Bone and Mineral Metabolism, University of Kentucky, Lexington, Kentucky, USA.

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
NCATS NIH HHS UL1 TR001998
6 · The paper itself

Abstract

introductionEarly rehabilitation in critically ill patients is associated with improved outcomes. Recent research demonstrates that patients requiring continuous renal replacement therapy (CRRT) can safely engage in mobility. The purpose of this study was to assess safety and feasibility of early rehabilitation with focus on mobility in patients requiring CRRT.

methodsStudy design was a mixed methods analysis of a quality improvement protocol. The setting was an intensive care unit (ICU) at a tertiary medical center. Safety was prospectively recorded by incidence of major adverse events including dislodgement of CRRT catheter, accidental extubation, bleeding, and hemodynamic emergency; and minor adverse events such as transient oxygen desaturation >10% of resting. Limited efficacy testing was performed to determine if rehabilitation parameters were associated with clinical outcomes.

resultsA total of 67 patients (54.0 ± 15.6 years old, 44% women, body mass index 29.2 ± 9.3 kg/m

conclusionsThe provision of early rehabilitation in critically ill patients requiring CRRT is safe and feasible. Further, these preliminary results suggest that early rehabilitation with focus on mobility may improve patient outcomes in this susceptible population.

Indexed as

continuous renal replacement therapycritical illnessCRRTearly rehabilitationquality improvement

Identifiers

PMID31922059
PMCPMC6943757

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.