Evidence map›Paper›PMID 31922057›Full record

ArticleKidney international reports2020

Preoperative Comorbidities and Outcomes of Medically Complex Living Kidney Donors.

Takahisa Hiramitsu, Toshihide Tomosugi, Kenta Futamura, Manabu Okada, Makoto Tsujita, Norihiko Goto, Toshihiro Ichimori, Shunji Narumi, Asami Takeda, Yoshihiko Watarai

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Long-Term Outcomes Across Age and Risk Profiles in a Caucasian Living Kidney Donor Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Takahisa HiramitsuDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Toshihide TomosugiDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Kenta FutamuraDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Manabu OkadaDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Makoto TsujitaDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Norihiko GotoDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Toshihiro IchimoriDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Shunji NarumiDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Asami TakedaDepartment of Nephrology, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Yoshihiko WataraiDepartment of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Showa-ku, Nagoya, Aichi, Japan.
Japanese Red Cross Nagoya Daini Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecent reports have described an increased risk of renal disease in living kidney donors compared with the general population. However, these reports do not detail the outcomes of medically complex living donors (MCLDs) with preoperative comorbidities (PCs), such as hypertension, dyslipidemia, glucose intolerance, and obesity. Analysis of living donors with end-stage renal disease (ESRD) has shown that these PCs may contribute significantly to the development of ESRD. We aimed to evaluate the effect of PCs on postoperative renal function and mortality in MCLDs.

methodsBetween January 2008 and December 2016, 807 living-donor kidney transplants were performed in our unit. Of these, 802 donors completed postoperative follow-up of >5 months. Donors were stratified into 4 groups based on the number of PCs present: healthy living donors (HLDs) with no PCs (

resultsInterstitial fibrosis, tubular atrophy, glomerulosclerosis, and arteriolosclerosis were more frequent in MCLDs (PC 3) than in HLDs. No significant differences were identified between HLDs and MCLDs in terms of postoperative eGFR and short-term mortality. Overt proteinuria and ESRD were not observed.

conclusionsAppropriate postdonation management of MCLDs with PCs may result in similar outcomes as for HLDs.

Indexed as

baseline biopsyestimated glomerular filtration ratekidney transplantationmedically complex living donorpreoperative comorbiditiesproteinuria

Identifiers

PMID31922057
PMCPMC6943774
OpenAlexW2980072342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.