Evidence map›Paper›PMID 31921840›Full record

ArticleFrontiers in cell and developmental biology2019

Infrapatellar Fat Pad Stem Cells Responsiveness to Microenvironment in Osteoarthritis: From Morphology to Function.

Elena Stocco, Silvia Barbon, Monica Piccione, Elisa Belluzzi, Lucia Petrelli, Assunta Pozzuoli, Roberta Ramonda, Marco Rossato, Marta Favero, Pietro Ruggieri and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. [Research progress of infrapatellar fat pad derived mesenchymal stem cells in treatment of osteoarthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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  13. Exosome miR-4738-3p-mediated regulation ofBiomolecules & biomedicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Elena StoccoDepartment of Neurosciences, Institute of Human Anatomy, University of Padova, Padua, Italy.
Silvia BarbonDepartment of Neurosciences, Institute of Human Anatomy, University of Padova, Padua, Italy.
Monica PiccioneDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Padua, Italy.
Elisa BelluzziMusculoskeletal Pathology and Oncology Laboratory, Department of Surgery, Oncology and Gastroenterology DiSCOG, University of Padova, Padua, Italy.
Lucia PetrelliDepartment of Neurosciences, Institute of Human Anatomy, University of Padova, Padua, Italy.
Assunta PozzuoliMusculoskeletal Pathology and Oncology Laboratory, Department of Surgery, Oncology and Gastroenterology DiSCOG, University of Padova, Padua, Italy.
Roberta RamondaRheumatology Unit, Department of Medicine - DIMED, University Hospital of Padova, Padua, Italy.
Marco RossatoClinica Medica 3, Department of Medicine - DIMED, University of Padova, Padua, Italy.
Marta FaveroRheumatology Unit, Department of Medicine - DIMED, University Hospital of Padova, Padua, Italy.
Pietro RuggieriDepartment of Orthopaedics and Orthopaedic Oncology, University of Padova, Padua, Italy.
Andrea PorzionatoDepartment of Neurosciences, Institute of Human Anatomy, University of Padova, Padua, Italy.
Rosa Di LiddoFoundation for Biology and Regenerative Medicine, Tissue Engineering and Signaling ONLUS, Padua, Italy.
Raffaele De CaroDepartment of Neurosciences, Institute of Human Anatomy, University of Padova, Padua, Italy.
Veronica MacchiDepartment of Neurosciences, Institute of Human Anatomy, University of Padova, Padua, Italy.
University of Padua · ITConsorzio per la Ricerca Sanitaria · ITFoundation for Cardiovascular Biomedical Research and Gene and Cell Therapy · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, infrapatellar fat pad (IFP) has been considered as a source of stem cells for cartilage regeneration in osteoarthritis (OA) due to their ability for differentiation into chondrocytes. However, stressful conditions, like that related to OA, may induce a pathogenic reprograming. The aim of this study was to characterize the structural and functional properties of a new population of stem cells isolated from osteoarthritic infrapatellar fat pad (OA-IFP). Nine OA patients undergoing total knee arthroplasty (TKA) were enrolled in this study [median age = 74 years, interquartile range (IQR) = 78.25-67.7; median body mass index = 29.4 Kg/m

Indexed as

inflammationinfrapatellar fat padosteoarthritisreprogramingstem cells

Identifiers

PMID31921840
PMCPMC6914674
OpenAlexW2989825178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.