Evidence map›Paper›PMID 31921825›Full record

ArticleFrontiers in bioengineering and biotechnology2019

Human Osteoblast Migration in DC Electrical Fields Depends on Store Operated Ca

Marco Rohde, Josefin Ziebart, Timo Kirschstein, Tina Sellmann, Katrin Porath, Friederike Kühl, Bachir Delenda, Christian Bahls, Ursula van Rienen, Rainer Bader and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Marco RohdeRostock University Medical Center, Oscar-Langendorff-Institute of Physiology, Rostock, Germany.
Josefin ZiebartBiomechanics and Implant Research Lab, Department of Orthopedics, Rostock University Medical Center, Rostock, Germany.
Timo KirschsteinRostock University Medical Center, Oscar-Langendorff-Institute of Physiology, Rostock, Germany.
Tina SellmannRostock University Medical Center, Oscar-Langendorff-Institute of Physiology, Rostock, Germany.
Katrin PorathRostock University Medical Center, Oscar-Langendorff-Institute of Physiology, Rostock, Germany.
Friederike KühlRostock University Medical Center, Oscar-Langendorff-Institute of Physiology, Rostock, Germany.
Bachir DelendaFaculty of Computer Science and Electrical Engineering, Institute of General Electrical Engineering, University of Rostock, Rostock, Germany.
Christian BahlsFaculty of Computer Science and Electrical Engineering, Institute of General Electrical Engineering, University of Rostock, Rostock, Germany.
Ursula van RienenFaculty of Computer Science and Electrical Engineering, Institute of General Electrical Engineering, University of Rostock, Rostock, Germany.
Rainer BaderBiomechanics and Implant Research Lab, Department of Orthopedics, Rostock University Medical Center, Rostock, Germany.
Rüdiger KöhlingRostock University Medical Center, Oscar-Langendorff-Institute of Physiology, Rostock, Germany.
University of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fracture healing and bone regeneration, particularly in the elderly, remains a challenge. There is an ongoing search for methods to activate osteoblasts, and the application of electrical fields is an attractive approach in this context. Although it is known that such electromagnetic fields lead to osteoblast migration and foster mesenchymal osteogenic differentiation, so far the mechanisms of osteoblast activation remain unclear. Possible mechanisms could rely on changes in Ca

Indexed as

bone regenerationcell migrationgalvanotaxisosteoblastsTRP channels

Identifiers

PMID31921825
PMCPMC6920109
OpenAlexW2993524467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.