Evidence map›Paper›PMID 31921690›Full record

ArticleFrontiers in oncology2019

Investigation of the Prognostic Significance of Vasculogenic Mimicry and Its Inhibition by Sorafenib in Canine Mammary Gland Tumors.

Maria Carolina Mangini Prado, Sofia de Almeida Losant Macedo, Giulia Gumiero Guiraldelli, Patricia de Faria Lainetti, Antonio Fernando Leis-Filho, Priscila Emiko Kobayashi, Renee Laufer-Amorim, Carlos Eduardo Fonseca-Alves

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

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  9. In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry.Methods in molecular biology (Clifton, N.J.) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Maria Carolina Mangini PradoDepartment of Veterinary Surgery and Anesthesiology, São Paulo State University-UNESP, Botucatu, Brazil.
Sofia de Almeida Losant MacedoDepartment of Veterinary Surgery and Anesthesiology, São Paulo State University-UNESP, Botucatu, Brazil.
Giulia Gumiero GuiraldelliDepartment of Veterinary Clinic, São Paulo State University-UNESP, Botucatu, Brazil.
Patricia de Faria LainettiDepartment of Veterinary Surgery and Anesthesiology, São Paulo State University-UNESP, Botucatu, Brazil.
Antonio Fernando Leis-FilhoDepartment of Veterinary Surgery and Anesthesiology, São Paulo State University-UNESP, Botucatu, Brazil.
Priscila Emiko KobayashiDepartment of Veterinary Clinic, São Paulo State University-UNESP, Botucatu, Brazil.
Renee Laufer-AmorimDepartment of Veterinary Clinic, São Paulo State University-UNESP, Botucatu, Brazil.
Carlos Eduardo Fonseca-AlvesDepartment of Veterinary Surgery and Anesthesiology, São Paulo State University-UNESP, Botucatu, Brazil.
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine mammary gland tumor (CMT) is one of the most important tumors in intact female dogs, and due its similarity to human breast cancer (BC), it is considered a model in comparative oncology. A subset of mammary gland tumors can show aggressive behavior, and a recurrent histological finding is the presence of vasculogenic mimicry (VM). VM is a process in which highly aggressive cancer cells fuse, forming fluid-conducting channels without endothelial cells. Although, VM has been described in canine inflammatory carcinoma, no previous studies have investigated the prognostic and predictive significance of VM in CMT. Thus, this research aimed to investigate the prognostic significance of VM

Indexed as

angiogenesisantiangiogenic drugsbreast cancerdogtubular assay

Identifiers

PMID31921690
PMCPMC6930929
OpenAlexW2995873011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.