Evidence map›Paper›PMID 31921526›Full record

ArticleBeilstein journal of nanotechnology2019

Small protein sequences can induce cellular uptake of complex nanohybrids.

Jan-Philip Merkl, Malak Safi, Christian Schmidtke, Fadi Aldeek, Johannes Ostermann, Tatiana Domitrovic, Sebastian Gärtner, John E Johnson, Horst Weller, Hedi Mattoussi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Beilstein journal of nanotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jan-Philip MerklDepartment of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United States.ORCID https://orcid.org/0000-0003-4856-967X
Malak SafiDepartment of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United States.
Christian SchmidtkeInstitute of Physical Chemistry; University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.
Fadi AldeekDepartment of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United States.
Johannes OstermannInstitute of Physical Chemistry; University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.
Tatiana DomitrovicInstituto de Microbiologia Paulo de Goes, Universidade Federal do Rio de Janeiro, 310. Lab I014, 21941-902, Rio de Janeiro, Brazil.
Sebastian GärtnerInstitute of Physical Chemistry; University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.
John E JohnsonThe Scripps Research Institute, Department of Integrative Structural and Computational Biology, MB31, La Jolla, California 92037, United States.
Horst WellerInstitute of Physical Chemistry; University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.
Hedi MattoussiDepartment of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this letter, we report on the ability of functional fusion proteins presenting a lytic gamma peptide, to promote interactions with HeLa cells and delivery of large hybrid nanostructures.

Indexed as

bioconjugationcellular uptakenanoparticle hybridspolymer encapsulationself-assembly

Identifiers

PMID31921526
PMCPMC6941447

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.