Evidence map›Paper›PMID 31921387›Full record

ArticleOncotarget2019

Effects of neoadjuvant FOLFIRINOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma.

Li Xie, Leizhou Xia, Ulla Klaiber, Milena Sachsenmaier, Ulf Hinz, Frank Bergmann, Oliver Strobel, Markus W Büchler, John P Neoptolemos, Franco Fortunato and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Necroptosis in pancreatic cancer: Molecular mechanisms and therapeutic implications.Apoptosis : an international journal on programmed cell death · 2026
    Pooled it
  2. Review
  3. Article
  4. Farnesoid X receptor activation inhibits pancreatic carcinogenesis.Biochimica et biophysica acta. Molecular basis of disease · 2023
    Article
  5. Article
  6. Necroptosis activation is associated with greater methylene blue-photodynamic therapy-induced cytotoxicity in human pancreatic ductal adenocarcinoma cells.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Targeting Autophagy in Breast Cancer.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Li XieDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
Leizhou XiaDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
Ulla KlaiberDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
Milena SachsenmaierDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
Ulf HinzDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
Frank BergmannInstitute of Pathology, University Clinic, Heidelberg, Germany.
Oliver StrobelDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
Markus W BüchlerDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
John P NeoptolemosDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
Franco FortunatoDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
Thilo HackertDepartment of General, Visceral and Transplantation Surgery, University Clinic, Heidelberg, Germany.
University Hospital Heidelberg · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

autophagycell deathneoadjuvant therapyprognosisstroma

Identifiers

PMID31921387
PMCPMC6944451
OpenAlexW2997016774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.