Evidence map›Paper›PMID 31921216›Full record

ArticleFrontiers in immunology2019

Genetic Modification of CD8

Teresa Lozano, Silvia Chocarro, Celia Martin, Aritz Lasarte-Cia, Cynthia Del Valle, Marta Gorraiz, Patricia Sarrión, Marina Ruiz de Galarreta, Amaia Lujambio, Sandra Hervás-Stubbs and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  3. EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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  4. Phosphatidylserine as a tumor target for CAR-T cell therapy.Journal for immunotherapy of cancer · 2025
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  5. Review
  6. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
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  10. Microbiology spectrum · 2024
    Article
  11. Article
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  13. Article
  14. Article
  15. Article
  16. Article
  17. Cellular based immunotherapy for primary liver cancer.Journal of experimental & clinical cancer research : CR · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Teresa LozanoImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Silvia ChocarroImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Celia MartinImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Aritz Lasarte-CiaImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Cynthia Del ValleImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Marta GorraizImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Patricia SarriónImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Marina Ruiz de GalarretaDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Amaia LujambioDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Sandra Hervás-StubbsImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Pablo SarobeImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Noelia CasaresImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Juan J LasarteImmunology and Immunotherapy Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Universidad de Navarra · ESIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adoptive immunotherapy with

Indexed as

Adoptive TransferCD8-Positive T-LymphocytesErbB ReceptorsGenetic VectorsNeoplasmsRetroviridaeTransduction, GeneticAnimalsCell Line, TumorFemaleMiceNeoplasm ProteinsEGFR protein, mouseErbB ReceptorsNeoplasm Proteinsadoptive cell therapyCD8+ T cellsEGFR ligandsepidermal growth factor receptor EGFRgenetic modificationhepatocellular carcinomatumor microenvironment

Identifiers

PMID31921216
PMCPMC6934060
OpenAlexW2996262293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.