Evidence map›Paper›PMID 31921158›Full record

ReviewFrontiers in immunology2019

Interleukin-7 Receptor Alpha in Innate Lymphoid Cells: More Than a Marker.

Abdalla Sheikh, Ninan Abraham

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. IL-23 Promotes γδT Cell Activity in Dry Eye Disease Progression.Investigative ophthalmology & visual science · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Human CD127 negative ILC2s show immunological memory.The Journal of experimental medicine · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Ischemia reperfusion injury facilitates lung allograft acceptance through IL-33-mediated activation of donor-derived IL-5 producing group 2 innate lymphoid cells.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  18. Review
  19. Review
  20. SARS-CoV-2 and HIV-1: So Different yet so AlikeInternational journal of medical sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Abdalla SheikhDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.
Ninan AbrahamDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.
University of British Columbia · CA

Funding

Canadian Institutes for Health Research MOP-126060Canadian Institutes for Health Research PJT-156119
6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) are a group of immune cells that are important for defense against pathogens, tissue repair, and lymphoid organogenesis. They share similar characteristics with various subsets of helper T cells but lack specific antigen receptors. Interleukin-7 (IL-7) and thymic stromal lymphopoietin (TSLP) are cytokines that engage the IL-7Rα and have major roles in dictating the fate of ILCs. Recent advances in the field have revealed transcriptional programs associated with ILC development and function. In this article, we will review recent studies of the role of IL-7 and TSLP in ILC development and function during infection and inflammation.

Indexed as

Immunity, InnateAnimalsCytokinesHumansInfectionsInflammationInterleukin-7LymphocytesReceptors, Interleukin-7Thymic Stromal LymphopoietinCytokinesIL7 protein, humanInterleukin-7interleukin-7 receptor, alpha chainReceptors, Interleukin-7Thymic Stromal LymphopoietinTSLP protein, humanIL-7inflammationinnate lymphoid cellslymphopoiesismucosal immunityTSLP

Identifiers

PMID31921158
PMCPMC6917604
OpenAlexW2990668369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.