ArticleFrontiers in immunology2019
Docosahexaenoic Acid Consumption Impedes Early Interferon- and Chemokine-Related Gene Expression While Suppressing Silica-Triggered Flaring of Murine Lupus.
Open access · goldAbstract read
In one paragraph
Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Results from omic approaches in rat or mouse models exposed to inhaled crystalline silica: a systematic review.Particle and fibre toxicology · 2024Pooled it
- Exposure to silicates and systemic autoimmune-related outcomes in rodents: a systematic review.Particle and fibre toxicology · 2022Pooled it
- Dietary and Nutritional Factors in Systemic Lupus Erythematosus Pathophysiology: A Scoping Review of the Evidence from In Vitro, In Vivo, and Human Studies.Advances in nutrition (Bethesda, Md.) · 2026Article
- Reducing Glucocorticoid Burden in Lupus with Omega-3 Fatty Acids: Docosahexaenoic Acid Augments Prednisone Efficacy in Maintaining Cyclophosphamide-Induced Remission of Preclinical Lupus Nephritis.bioRxiv : the preprint server for biology · 2026Article
- Skeletal muscle lncRNA profile associated with fatty acids in Nellore beef cattle.Scientific reports · 2025Article
- Occupational dust and chemical exposures and the development of autoimmune rheumatic diseases.Nature reviews. Rheumatology · 2025Review
- Omega-3 fatty acid synergy with glucocorticoid in mouse lupus macrophage model: targeting pathogenic pathways to reduce steroid dependence.Frontiers in immunology · 2025Article
- Crystalline silica-induced pulmonary inflammation and autoimmunity in mature adult NZBW/f1 mice: age-related sensitivity and impact of omega-3 fatty acid intervention.Inhalation toxicology · 2024Article
- The modulation of immune cell death in connection to microRNAs and natural products.Frontiers in immunology · 2024Review
- Serum fatty acid profiles in systemic lupus erythematosus and patient reported outcomes: The Michigan Lupus Epidemiology & Surveillance (MILES) Program.Frontiers in immunology · 2024Article
- Dietary docosahexaenoic acid supplementation inhibits acute pulmonary transcriptional and autoantibody responses to a single crystalline silica exposure in lupus-prone mice.Frontiers in immunology · 2024Article
- Crystalline silica-induced proinflammatory eicosanoid storm in novel alveolar macrophage model quelled by docosahexaenoic acid supplementation.Frontiers in immunology · 2023Article
- Lipidome modulation by dietary omega-3 polyunsaturated fatty acid supplementation or selective soluble epoxide hydrolase inhibition suppresses rough LPS-accelerated glomerulonephritis in lupus-prone mice.Frontiers in immunology · 2023Article
- β-caryophyllene and docosahexaenoic acid, isolated or associated, have potential antinociceptive and anti-inflammatory effects in vitro and in vivo.Scientific reports · 2022Article
- Low n-6/n-3 Gestation and Lactation Diets Influence Early Performance, Muscle and Adipose Polyunsaturated Fatty Acid Content and Deposition, and Relative Abundance of Proteins in Suckling Piglets.Molecules (Basel, Switzerland) · 2022Article
- Comparative effects of human-equivalent low, moderate, and high dose oral prednisone intake on autoimmunity and glucocorticoid-related toxicity in a murine model of environmental-triggered lupus.Frontiers in immunology · 2022Article
- Single cell analysis of docosahexaenoic acid suppression of sequential LPS-induced proinflammatory and interferon-regulated gene expression in the macrophage.Frontiers in immunology · 2022Article
- Lipid Metabolism: Immune Regulation and Therapeutic Prospectives in Systemic Lupus Erythematosus.Frontiers in immunology · 2022Review
- Rapid Induction of Pulmonary Inflammation, Autoimmune Gene Expression, and Ectopic Lymphoid Neogenesis Following Acute Silica Exposure in Lupus-Prone Mice.Frontiers in immunology · 2021Article
- Omega-3 Polyunsaturated Fatty Acid Intervention Against Established Autoimmunity in a Murine Model of Toxicant-Triggered Lupus.Frontiers in immunology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Abby D BenninghoffDepartment of Animal, Dairy and Veterinary Sciences and The School of Veterinary Medicine, Utah State University, Logan, UT, United States.
Melissa A BatesDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Preeti S ChauhanDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Kathryn A WierengaInstitute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Kristen N GilleyDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Andrij HolianDepartment of Biomedical and Pharmaceutical Sciences, Center for Environmental Health Sciences, University of Montana, Missoula, MT, United States.
Jack R HarkemaInstitute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
James J PestkaDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Michigan State University · USCenter for Environmental Health · USUtah State University · US
Funding
MULTIDISCIPLINARY TRAINING IN ENVIRONMENTAL TOXICOLOGYT32ES007255 · NIEHS · MICHIGAN STATE UNIVERSITY · PI JOHN J LAPRES · 1989 to 2026
$9.3MRole of alveolar macrophage in omega-3 fatty acid amelioration of silica-triggered autoimmunity.R01ES027353 · NIEHS · MICHIGAN STATE UNIVERSITY · PI Andrew Olive · 2017 to 2026
$4.8MOmega-3 Fatty Acid Suppression of Silica-induced Inflammasome Activation in a Novel Alveolar Macrophage ModelF31ES030593 · NIEHS · MICHIGAN STATE UNIVERSITY · PI WIERENGA, KATHRYN ALEXANDRIA · 2019 to 2021
$90kNIEHS NIH HHS F31 ES030593NIEHS NIH HHS R01 ES027353NIEHS NIH HHS T32 ES007255
Abstract
Exposure of lupus-prone female NZBWF1 mice to respirable crystalline silica (cSiO
Indexed as
Lupus Erythematosus, SystemicAnimalsChemokinesDocosahexaenoic AcidsFemaleGene Expression RegulationInterferonsMiceSilicon DioxideChemokinesDocosahexaenoic AcidsInterferonsSilicon Dioxideautoimmunitykidneylungnanostringomega-3 polyunsaturated fatty acidssilicasystemic lupus erythematosustranscriptome
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.