Evidence map›Paper›PMID 31921004›Full record

ReviewFrontiers in microbiology2019

Immune Biomarkers for Diagnosis and Treatment Monitoring of Tuberculosis: Current Developments and Future Prospects.

Yean K Yong, Hong Y Tan, Alireza Saeidi, Won F Wong, Ramachandran Vignesh, Vijayakumar Velu, Rajaraman Eri, Marie Larsson, Esaki M Shankar

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yean K YongLaboratory Center, Xiamen University Malaysia, Sepang, Malaysia.
Hong Y TanLaboratory Center, Xiamen University Malaysia, Sepang, Malaysia.
Alireza SaeidiDepartment of Pediatrics, Emory Vaccine Center, Atlanta, GA, United States.
Won F WongDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Ramachandran VigneshLaboratory Center, Xiamen University Malaysia, Sepang, Malaysia.
Vijayakumar VeluDepartment of Microbiology and Immunology, Emory Vaccine Center, Atlanta, GA, United States.
Rajaraman EriSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, TAS, Australia.
Marie LarssonDivision of Molecular Virology, Department of Clinical and Experimental Medicine, Linkoping University, Linkoping, Sweden.
Esaki M ShankarDivision of Infection Biology and Medical Microbiology, Department of Life Sciences, Central University of Tamil Nadu (CUTN), Thiruvarur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) treatment monitoring is paramount to clinical decision-making and the host biomarkers appears to play a significant role. The currently available diagnostic technology for TB detection is inadequate. Although GeneXpert detects total DNA present in the sample regardless live or dead bacilli present in clinical samples, all the commercial tests available thus far have low sensitivity. Humoral responses against

Indexed as

biomarkersdiagnosticsHIVtreatment monitoringtuberculosis

Identifiers

PMID31921004
PMCPMC6930807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.