Evidence map›Paper›PMID 31920967›Full record

ReviewFrontiers in endocrinology2019

Graves' Disease and the Post-partum Period: An Intriguing Relationship.

Laura Croce, Giulia Di Dalmazi, Francesca Orsolini, Camilla Virili, Giulia Brigante, Elena Gianetti, Mariacarla Moleti, Giorgio Napolitano, Massimo Tonacchera, Mario Rotondi

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Current concepts regarding Graves' orbitopathy.Journal of internal medicine · 2022
    Review
  3. Endocrine Autoimmunity in Pregnancy.Frontiers in immunology · 2022
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Laura CroceUnit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
Giulia Di DalmaziUnit of Endocrinology, Department of Medicine and Sciences of Aging, "G. D'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Francesca OrsoliniEndocrinology Section, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Camilla ViriliEndocrinology Unit, Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.
Giulia BriganteUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Elena GianettiEndocrinology Section, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Mariacarla MoletiDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Giorgio NapolitanoUnit of Endocrinology, Department of Medicine and Sciences of Aging, "G. D'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Massimo TonaccheraEndocrinology Section, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Mario RotondiUnit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
University of Pisa · ITUniversity of Chieti-Pescara · ITIstituti Clinici Scientifici Maugeri · ITSapienza University of Rome · ITUniversity of Messina · ITUniversity of Modena and Reggio Emilia · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The post-partum period is an immunologically peculiar period in a woman's life. Indeed, most of the pregnancy-related immune changes gradually revert in the 12 months following delivery. Although the post-partum period has long been identified as a period of aggravation of autoimmune thyroid diseases, most of the currently available studies took into account the relationship between post-partum and autoimmune thyroiditis. More recently, the potential repercussions of the post-partum period on Graves' disease were also taken into account. The present mini review will briefly overview the most recent advances in our knowledge of the immunology of the post-partum period in relation with the potential repercussions on the clinical course of Graves' disease. Moreover, some peculiar aspects of post-partum Graves' disease in terms of clinical and biochemical presentation, diagnostic challenges, and specific therapeutic considerations also taking into account the recommendation of the latest clinical guidelines on the management of thyroid diseases in pregnancy will be overviewed.

Indexed as

antithyroid drugsautoimmunityGraves' diseaseiodine deficiencylactationpost-partumpregnancythyroid

Identifiers

PMID31920967
PMCPMC6914725
OpenAlexW2991561545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.