ReviewFrontiers in psychology2019
Traumatic Events, Personality and Psychopathology in Takotsubo Syndrome: A Systematic Review.
Review in Frontiers in psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Heart rate variability alterations in takotsubo syndrome and related association with psychological factors: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Takotsubo syndrome: pathophysiological insights and innovations in patient care.Nature reviews. Cardiology · 2026Review
- Fuzzy boundaries between physical and emotional triggers in Takotsubo syndrome: a scoping review.BMC cardiovascular disorders · 2026Article
- When a Woman's Heart Fails to Contain: Takotsubo Syndrome as a Gendered Collapse of Emotional Regulation.Life (Basel, Switzerland) · 2025Review
- Psychosocial and clinical characteristics in Takotsubo syndrome.Biology of sex differences · 2025Article
- Loneliness and Social Isolation in Individuals with Acute Myocardial Infarction and Takotsubo Syndrome: A Scoping Review.Healthcare (Basel, Switzerland) · 2025Review
- Deciphering the Psychological Characteristics of Takotsubo Cardiomyopathy and Acute Myocardial Infarction.Journal of personalized medicine · 2024Article
- The heart-mind relationship in women cardiovascular primary prevention: the role of depression, anxiety, distress and Type-D personality in the 10-years cardiovascular risk evaluation.Frontiers in cardiovascular medicine · 2024Article
- Perceived Anxiety, Coping, and Autonomic Function in Takotsubo Syndrome Long after the Acute Event.Life (Basel, Switzerland) · 2022Article
- Psychosocial and clinical characteristics of a patient with Takotsubo syndrome and her healthy monozygotic twin: a case report.European heart journal. Case reports · 2022Article
- Update of Takotsubo cardiomyopathy: Present experience and outlook for the future.International journal of cardiology. Heart & vasculature · 2022Review
- Psychological Characteristics of Patients with Takotsubo Syndrome and Patients with Acute Coronary Syndrome: An Explorative Study toward a Better Personalized Care.Journal of personalized medicine · 2022Article
- Smidt Heart Institute Takotsubo Registry - Study design and baseline characteristics.American heart journal plus : cardiology research and practice · 2022Article
- Psychological Traumas and Cardiovascular Disease: A Case-Control Study.Healthcare (Basel, Switzerland) · 2021Article
- Takotsubo syndrome in COVID-19 era: Is psychological distress the key?Journal of psychosomatic research · 2021Article
- Editorial: Personality and Disease: New Directions in Modern Research.Frontiers in psychology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTakotsubo syndrome (TTS) is a transient heart disease that has been historically related to the occurrence of psychological (emotional) factors ("broken heart" syndrome). We aimed to conduct a systematic review analyzing the role of psychological factors in TTS.
methodsAll studies on TTS and psychological factors from January 1991 through April 2019 were scrutinized according to the Cochrane Collaboration and the PRISMA statements. Selected studies were additionally evaluated for the Risk of Bias according to the Newcastle-Ottawa Scale (NOS).
resultsFifteen case-control studies (by Mayo Clinic criteria) were finally selected. Most studies analyzed stressful life-events or trauma, although with conflicting findings, while a likely role of long-lasting psychological distress seemed to be a homogenous result. Among life-time psychopathology, only anxiety appeared to have a significant role. Some studies outlined a likely role of personality, but findings are conflicting.
conclusionOur findings do not lead to any definitive assumption on the specific role of psychological factors in TTS, also for scant strong methodology of the most part of the studies. More studies with stronger research methodology are needed to better characterize psychological elements in TTS.
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