Evidence map›Paper›PMID 31920743›Full record

ReviewFrontiers in psychiatry2019

Cognition and Related Neural Findings on Methamphetamine Use Disorder: Insights and Treatment Implications From Schizophrenia Research.

Alexandre A Guerin, Yvonne Bonomo, Andrew John Lawrence, Bernhard Theodor Baune, Eric J Nestler, Susan L Rossell, Jee Hyun Kim

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Midlife and Older Age Methamphetamine Poisoning Deaths in Hawai'i.Hawai'i journal of health & social welfare · 2024
    Article
  9. Review
  10. Article
  11. Associations between methamphetamine use disorder andDialogues in clinical neuroscience · 2024
    Article
  12. Article
  13. Leukocyte telomere length is not shortened in methamphetamine dependence or methamphetamine-induced psychosis but is increased following traumatic events.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Cognition during active methamphetamine use versus remission.Journal of clinical and experimental neuropsychology · 2021
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Alexandre A GuerinMental Health Theme, The Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.
Yvonne BonomoDepartment of Addiction Medicine, St Vincent's Hospital, Melbourne, VIC, Australia.
Andrew John LawrenceMental Health Theme, The Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.
Bernhard Theodor BauneDepartment of Psychiatry, University of Melbourne, Melbourne, VIC, Australia.
Eric J NestlerDepartment of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Susan L RossellCentre for Mental Health, Swinburne University of Technology, Melbourne, VIC, Australia.
Jee Hyun KimMental Health Theme, The Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.
Mental Health Australia · AUUniversity of Melbourne · AUAllen Institute for Brain Science · USIcahn School of Medicine at Mount Sinai · USSt Vincent's Hospital · AU

Funding

Transcription Factors in Stimulant and Opioid ActionP01DA047233 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI YASMIN L. HURD · 2019 to 2026
$16.5M
NIDA NIH HHS P01 DA047233
6 · The paper itself

Abstract

Despite the prevalence of methamphetamine (meth) use disorder, research on meth is disproportionately scarce compared to research on other illicit drugs. Existing evidence highlights cognitive deficits as an impediment against daily function and treatment of chronic meth use. Similar deficits are also observed in schizophrenia, and this review therefore draws on schizophrenia research by examining similarities and differences between the two disorders on cognition and related neural findings. While meth use disorder and schizophrenia are two distinct disorders, they are highly co-morbid and share impairments in similar cognitive domains and altered brain structure/function. This narrative review specifically identifies overlapping features such as deficits in learning and memory, social cognition, working memory and inhibitory/impulse control. We report that while working memory deficits are a core feature of schizophrenia, such deficits are inconsistently observed following chronic meth use. Similar structural and functional abnormalities are also observed in cortical and limbic regions between the two disorders, except for cingulate activity where differences are observed. There is growing evidence that targeting cognitive symptoms may improve functional outcome in schizophrenia, with evidence of normalized abnormal brain activity in regions associated with cognition. Considering the overlap between meth use disorder and schizophrenia, targeting cognitive symptoms in people with meth use disorder may also improve treatment outcome and daily function.

Indexed as

braincognitionmemorymethamphetamine use disorderMRIschizophrenia

Identifiers

PMID31920743
PMCPMC6928591
OpenAlexW2996116995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.