Evidence map›Paper›PMID 31920740›Full record

ReviewFrontiers in psychiatry2019

A Roadmap for Integrating Neuroscience Into Addiction Treatment: A Consensus of the Neuroscience Interest Group of the International Society of Addiction Medicine.

Antonio Verdejo-Garcia, Valentina Lorenzetti, Victoria Manning, Hugh Piercy, Raimondo Bruno, Rob Hester, David Pennington, Serenella Tolomeo, Shalini Arunogiri, Marsha E Bates and 16 more

Abstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Addiction Education in the Undergraduate Space: A Novel Course Connecting Neurobiology of Addiction and Compassion for Individuals with Substance Use Disorder.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2025
    Article
  11. Review
  12. Article
  13. Neuroimaging Biomarkers in Addiction.medRxiv : the preprint server for health sciences · 2024
    Article
  14. Substance Addiction Rehabilitation Drugs.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Antonio Verdejo-GarciaTurner Institute for Brain and Mental Health, Monash University, Melbourne, VIC, Australia.
Valentina LorenzettiSchool of Psychology, Faculty of Health Sciences, Australian Catholic University, Canberra, ACT, Australia.
Victoria ManningEastern Health Clinical School Turning Point, Eastern Health, Richmond, VIC, Australia.
Hugh PiercyEastern Health Clinical School Turning Point, Eastern Health, Richmond, VIC, Australia.
Raimondo BrunoSchool of Medicine, University of Tasmania, Hobart, TAS, Australia.
Rob HesterSchool of Psychological Sciences, University of Melbourne, Melbourne, VIC, Australia.
David PenningtonSan Francisco Veterans Affairs Health Care System (SFVAHCS), San Francisco, CA, United States.
Serenella TolomeoSchool of Medicine, University of St Andrews, Medical and Biological Science Building, North Haugh, St Andrews, United Kingdom.
Shalini ArunogiriEastern Health Clinical School Turning Point, Eastern Health, Richmond, VIC, Australia.
Marsha E BatesDepartment of Kinesiology and Health, Rutgers University, New Brunswick, NJ, United States.
Henrietta Bowden-JonesDepartment of Medicine, Faculty of Medicine, Imperial College, London, United Kingdom.
Salvatore CampanellaLaboratoire de Psychologie Médicale et d'Addictologie, ULB Neuroscience Institute (UNI), CHU Brugmann-Université Libre de Bruxelles (U.L.B.), Brussels, Belgium.
Stacey B DaughtersDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Christos KouimtsidisDepartment of Psychiatry, Surrey and Borders Partnership NHS Foundation Trust, Leatherhead, United Kingdom.
Dan I LubmanEastern Health Clinical School Turning Point, Eastern Health, Richmond, VIC, Australia.
Dieter J MeyerhoffDVA Medical Center and Department of Radiology and Biomedical Imaging, University of California San Francisco, School of Medicine, San Francisco, CA, United States.
Annaketurah RalphSchool of Psychology, University of Queensland, Brisbane, QLD, Australia.
Tara RezapourDepartment of Cognitive Psychology, Institute for Cognitive Sciences Studies, Tehran, Iran.
Hosna TavakoliDepartment of Cognitive Psychology, Institute for Cognitive Sciences Studies, Tehran, Iran.
Mehran Zare-BidokyIranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran.
Anna ZilverstandDepartment of Psychiatry, University of Minnesota, Minneapolis, MN, United States.
Douglas SteeleMedical School, University of Dundee, Ninewells Hospital, Scotland, United Kingdom.
Scott J MoellerDepartment of Psychiatry, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, United States.
Martin PaulusLaureate Institute for Brain Research, University of Tulsa, Tulsa, OK, United States.
Alex BaldacchinoDepartment of Psychiatry, University of California, San Francisco, San Francisco, CA, United States.
Hamed EkhtiariLaureate Institute for Brain Research, University of Tulsa, Tulsa, OK, United States.

Funding

Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
Project IMPACT: In-the-Moment Protection from Automatic Capture by TriggersR01AA023667 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI BATES, MARSHA E., BUCKMAN, JENNIFER F. · 2015 to 2019
$2.7M
Neural Links of Approach Bias Modification in Heavy Drinking VeteransIK2CX001510 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI PENNINGTON, DAVID L · 2017 to 2022
–
CSRD VA IK2 CX001510NIAAA NIH HHS R01 AA023667NICHD NIH HHS R25 HD045810NIMH NIH HHS R25 MH067127
6 · The paper itself

Abstract

Although there is general consensus that altered brain structure and function underpins addictive disorders, clinicians working in addiction treatment rarely incorporate neuroscience-informed approaches into their practice. We recently launched the Neuroscience Interest Group within the International Society of Addiction Medicine (ISAM-NIG) to promote initiatives to bridge this gap. This article summarizes the ISAM-NIG key priorities and strategies to achieve implementation of addiction neuroscience knowledge and tools for the assessment and treatment of substance use disorders. We cover two assessment areas: cognitive assessment and neuroimaging, and two interventional areas: cognitive training/remediation and neuromodulation, where we identify key challenges and proposed solutions. We reason that incorporating cognitive assessment into clinical settings requires the identification of constructs that predict meaningful clinical outcomes. Other requirements are the development of measures that are easily-administered, reliable, and ecologically-valid. Translation of neuroimaging techniques requires the development of diagnostic and prognostic biomarkers and testing the cost-effectiveness of these biomarkers in individualized prediction algorithms for relapse prevention and treatment selection. Integration of cognitive assessments with neuroimaging can provide multilevel targets including neural, cognitive, and behavioral outcomes for neuroscience-informed interventions. Application of neuroscience-informed interventions including cognitive training/remediation and neuromodulation requires clear pathways to design treatments based on multilevel targets, additional evidence from randomized trials and subsequent clinical implementation, including evaluation of cost-effectiveness. We propose to address these challenges by promoting international collaboration between researchers and clinicians, developing harmonized protocols and data management systems, and prioritizing multi-site research that focuses on improving clinical outcomes.

Indexed as

addiction medicinecognitive rehabilitationfMRIneuromodulationneuropsychological assessmentneurosciencesubstance use disordertreatment

Identifiers

PMID31920740
PMCPMC6935942

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.