Evidence map›Paper›PMID 31920633›Full record

ArticleFrontiers in pharmacology2019

Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model.

Dieter V Van de Sande, Ivan Kopljar, Ard Teisman, David J Gallacher, Dirk J Snyders, Hua Rong Lu, Alain J Labro

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dieter V Van de SandeLaboratory of Molecular, Cellular, and Network Excitability, University of Antwerp, Antwerp, Belgium.
Ivan KopljarLaboratory of Molecular, Cellular, and Network Excitability, University of Antwerp, Antwerp, Belgium.
Ard TeismanGlobal Safety Pharmacology, Non-Clinical Safety, Janssen R&D, Beerse, Belgium.
David J GallacherGlobal Safety Pharmacology, Non-Clinical Safety, Janssen R&D, Beerse, Belgium.
Dirk J SnydersLaboratory of Molecular, Cellular, and Network Excitability, University of Antwerp, Antwerp, Belgium.
Hua Rong LuGlobal Safety Pharmacology, Non-Clinical Safety, Janssen R&D, Beerse, Belgium.
Alain J LabroLaboratory of Molecular, Cellular, and Network Excitability, University of Antwerp, Antwerp, Belgium.
University of Antwerp · BEJanssen (Belgium) · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cardiac Nav1.5 mediated sodium current (I

Indexed as

arrhythmicflecainidelidocainepatch-clampphenytoinquinidineSCN5A

Identifiers

PMID31920633
PMCPMC6917651
OpenAlexW2995325597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.