Evidence map›Paper›PMID 31920557›Full record

ArticleFrontiers in cellular neuroscience2019

Kv7.4 Channel Contribute to Projection-Specific Auto-Inhibition of Dopamine Neurons in the Ventral Tegmental Area.

Min Su, Li Li, Jing Wang, Hui Sun, Ludi Zhang, Chen Zhao, Ying Xie, Nikita Gamper, Xiaona Du, Hailin Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. KAddiction biology · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Autism-associated mutations in KProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Article
  9. Kv7 Channels and Excitability Disorders.Handbook of experimental pharmacology · 2021
    Article
  10. The Role of KFrontiers in physiology · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Min SuDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Li LiDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Jing WangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Hui SunDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Ludi ZhangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Chen ZhaoDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Ying XieCenter for the Experimental Animal, Hebei Medical University, Shijiazhuang, China.
Nikita GamperDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Xiaona DuDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Hailin ZhangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CNMinistry of Education of the People's Republic of China · CNHebei University of Chinese Medicine · CNUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopaminergic neurons in the ventral tegmental area (VTA) encode behavioral patterns important in reward and drug addiction as well as in emotional disorders. These functions of dopamine neurons are directly related to the release of dopamine in the targeted regions of the brain which are, thus, controlled by the excitability of dopamine neurons. One mechanism for modulation of dopamine neuronal excitability is mediated by the auto dopamine type 2 (D2) receptors, through activation of a Kir3/GIRK K

Indexed as

circuitD2 receptordopamine neuronKir3/GIRK channelKv7/M channelsneuronal excitabilityventral tegmental area

Identifiers

PMID31920557
PMCPMC6930245
OpenAlexW2996266132

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.