ArticleThe Saudi dental journal2020
Response of stem cells from human exfoliated deciduous teeth (SHED) to three bioinductive materials - An in vitro experimental study.
Article in The Saudi dental journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The trial behind it
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Who cites it
29 citing papers in PubMed, 44 citations in OpenAlex.
- Osteogenic Marker Expression after SHED and PMMA-HA Scaffold Application in Alveolar Bone Defects.European journal of dentistry · 2026Article
- Application of an MTT-Based Colorimetric Assay to Evaluate SHED Metabolites in Inhibiting Oral Bacteria Growth.European journal of dentistry · 2026Article
- Article
- Amelogenin Peptide Promotes Human Dental Pulp Cell Proliferation and Odontogenic Differentiation via ERK1/2 Pathway.International dental journal · 2026Article
- Cytocompatibility of Three Calcium Silicate-Based Biomaterials: A Systematic Review and Meta-Analysis.Iranian endodontic journal · 2026Review
- Responses of stem cells isolated from human primary teeth to calcium-containing pulp capping materials.BMC oral health · 2025Article
- The Combination of Biomimetic Materials Enhances the Functional Differentiation of Stem Cells Exfoliated from Human Deciduous Teeth.International journal of clinical pediatric dentistry · 2025Article
- Cytotoxicity and proliferation effects of cold ceramic on stem cells from human exfoliated deciduous teeth compared to MTA: an in vitro study.BMC oral health · 2025Article
- Cytotoxic Effects of Pulp Capping Agents on Mesenchymal Stem Cells Isolated from Human Exfoliated Deciduous Teeth.Journal of dentistry (Shiraz, Iran) · 2024Article
- Article
- Exploring vital pulp Therapies: A bibliometric analysis of the most cited articles.The Saudi dental journal · 2024Article
- Effect of pulp capping materials on odontogenic differentiation of human dental pulp stem cells: An in vitro study.Clinical and experimental dental research · 2024Article
- Evaluation of dental pulp stem cells response to flowable nano-hybrid dental composites: A comparative analysis.PloS one · 2024Article
- Cytotoxicity of dilutions of bioceramic materials in stem cells of human exfoliated deciduous teeth.Journal of applied oral science : revista FOB · 2024Article
- Comparative biological properties of resin-free and resin-based calcium silicate-based endodontic repair materials on human periodontal ligament stem cells.Clinical oral investigations · 2023Article
- Biocompatibility and mineralization potential of new calcium silicate cements.Journal of dental sciences · 2023Article
- Application of neurotransmitters and dental stem cells for pulp regeneration: A review.The Saudi dental journal · 2023Review
- Effect of Different Sealers on the Cytocompatibility and Osteogenic Potential of Human Periodontal Ligament Stem Cells: An In Vitro Study.Journal of clinical medicine · 2023Article
- Analysis of Pulp Tissue Viability and Cytotoxicity of Pulp Capping Agents.Journal of clinical medicine · 2023Article
- Comparison of Biological Properties and Clinical Application of Mesenchymal Stem Cells from the Mesoderm and Ectoderm.Stem cells international · 2023Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionStem cells have unmatched capacity and potential for regeneration and when used alone or in combination with scaffolds to replace or repair damaged cells, can differentiate into any mature cell.
aimTo evaluate the functional differentiation potential of EMD (Enamel Matrix Derivative), MTA (Mineral Trioxide Aggregate) and Biodentine on Stem Cells from Human Exfoliated Deciduous teeth (SHED).
objectiveTo determine functional differentiation potential (osteogenic/odontogenic) of various biomaterials on SHED. MATERIAL AND
methodSHED derived from 5
resultsIt was observed that EMD imparted the highest cell viability at the end of 7 days (p < 0.001) followed by Biodentine and MTA. Likewise EMD showed highest potential to enhanced mineralization and expression of dentine sialoprotein (p < 0.001) followed by Biodentine and MTA at the end of 14 days (p<0.001).
conclusionIt can be concluded that all the tested materials are bioinductive to SHED. EMD can be used for various vital pulp therapies as that of Biodentine and MTA with predictable as well as enhanced success rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.