Evidence map›Paper›PMID 31919754›Full record

ReviewMolecular diagnosis & therapy2020

Liquid Biopsy Applications in the Clinic.

Dake Chen, Tao Xu, Shubin Wang, Howard Chang, Tao Yu, Yu Zhu, Jian Chen

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Molecular diagnosis & therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Personalized treatment approach for HER2-positive metastatic breast cancer.Medical oncology (Northwood, London, England) · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Liquid Biopsy in Adverse Neurodevelopment of Children: Problems and Prospects.Methods in molecular biology (Clifton, N.J.) · 2023
    Review
  13. Review
  14. Role of Liquid Biopsies in Rheumatoid Arthritis.Methods in molecular biology (Clifton, N.J.) · 2023
    Review
  15. Article
  16. The road-map for establishment of a prognostic molecular marker panel in glioma using liquid biopsy: current status and future directions.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dake ChenDepartment of Oncology, Tongzhou People's Hospital, Nantong, 226300, China.
Tao XuDepartment of Anesthesiology, Affiliated Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200233, China.
Shubin WangDepartment of Oncology, Peking University-Shenzhen Hospital, Shenzhen, China.
Howard ChangCuraCloud Corporation, 999 Third Ave, Suite 700, Seattle, WA, 98104, USA.
Tao YuCuraCloud Corporation, 999 Third Ave, Suite 700, Seattle, WA, 98104, USA. taoy@curacloudcorp.com.ORCID 0000-0002-2590-1513
Yu ZhuDepartment of Oncology, Peking University-Shenzhen Hospital, Shenzhen, China. yuzhu5@hotmail.com.
Jian ChenDepartment of Orthopedics, Tongzhou People's Hospital, Nantong, 226300, China. tzcj@nttzhospital.com.
Peking University Shenzhen Hospital · CNNantong University · CNShanghai Jiao Tong University · CNUniversal Alloy (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global liquid biopsy industry is expected to exceed $US5 billion by 2023. One application of liquid biopsy technology is the diagnosis of disease using biomarkers found in blood, urine, stool, saliva, and other biological samples from patients. These biomarkers could be DNA, RNA, protein, or even a cell. More recently, the use of cell-free DNA from plasma is emerging as an important minimally invasive tool for clinical diagnosis. The development of technology has increased the diversity of its application. Here, we discuss how liquid biopsies have been used in the clinic, and how personalized medicine are likely to use liquid biopsies in the near future.

Indexed as

BiomarkersEarly DiagnosisHumansLiquid BiopsyNeoplasm, ResidualPrecision MedicineBiomarkers

Identifiers

PMID31919754
OpenAlexW2999524222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.