Evidence map›Paper›PMID 31919716›Full record

ReviewSleep & breathing = Schlaf & Atmung2020

Obstructive sleep apnea and cardiovascular disease, a story of confounders!

Jacob Collen, Christopher Lettieri, Emerson Wickwire, Aaron Holley

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sleep & breathing = Schlaf & Atmung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. The effect of obstructive sleep apnea on the increased risk of cardiovascular disease: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Identification of OSAHS patients based on ReliefF-mRMR feature selection.Physical and engineering sciences in medicine · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jacob CollenUniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA. jacob.collen@usuhs.edu.ORCID http://orcid.org/0000-0002-8064-6391
Christopher LettieriUniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Emerson WickwireDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Aaron HolleyUniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Uniformed Services University of the Health Sciences · USUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) syndrome is increasingly common among middle aged and older adults and is frequently linked to most cardiovascular diseases (CVD). Sleep-disordered breathing and CVD share a number of common risk factors and comorbid conditions including obesity, male gender, advancing age, metabolic syndrome, and hypertension. OSA appears to be associated with worsened CVD outcomes, sleep-related symptoms, quality of life, and risk of motor vehicle accidents. Demonstrating a cause-and-effect relationship between CVD and OSA has been challenging due to shared comorbidities. Strong evidence demonstrating clinically significant benefit for OSA treatments on OSA-related CVD outcomes are limited. In this review, we evaluate potential pathophysiologic mechanisms that link OSA to CVD and focus on specific treatments for OSA, including positive airway pressure (PAP), dental devices, and surgeries with regard to OSA-related CVD outcomes.

Indexed as

Cardiovascular DiseasesContinuous Positive Airway PressureHumansRisk FactorsSleep Apnea, ObstructiveTreatment OutcomeAtrial fibrillationCardiovascular diseaseCerebrovascular accidentCerebrovascular diseaseCongestive heart failureContinuous positive airway pressureCoronary artery diseaseHypertensionObstructive sleep apneaPositive airway pressurePulmonary hypertension

Identifiers

PMID31919716
OpenAlexW2999688724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.