Evidence map›Paper›PMID 31919583›Full record

Trial reportEuropean journal of nutrition2020

Modest improvement in CVD risk markers in older adults following quinoa (Chenopodium quinoa Willd.) consumption: a randomized-controlled crossover study with a novel food product.

L Kirsty Pourshahidi, Eduardo Caballero, Alejandro Osses, Barry W Hyland, Nigel G Ternan, Chris I R Gill

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07513610 (The Effects of Dietary Quinoa and Buckwheat Consumption on Weight Management and Gut Microbiome), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07513610 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effects of Dietary Quinoa and Buckwheat Consumption on Weight Management and Gut Microbiome

TypeinterventionalSponsorHacettepe UniversityRan2024 to 2025Enrolled148ConditionsOverweight, ObesityArmsquinoa, Buckwheat, Rice, Bulgur wheat
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Blackcurrant (The British journal of nutrition · 2021
    Trial
  3. Effects of Different Dietary Levels of Chia (Food science & nutrition · 2026
    Article
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  7. Review
  8. Review
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

L Kirsty PourshahidiNutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine, BT52 1SA, UK.ORCID http://orcid.org/0000-0003-2251-5251
Eduardo CaballeroRegional Centre for Studies in Food and Health (CREAS), Avenida Universidad N°330, Valparaiso, Chile.
Alejandro OssesRegional Centre for Studies in Food and Health (CREAS), Avenida Universidad N°330, Valparaiso, Chile.
Barry W HylandSchool of Biomedical Sciences, Ulster University, Coleraine, BT52 1SA, UK.ORCID http://orcid.org/0000-0003-1380-0720
Nigel G TernanNutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine, BT52 1SA, UK.ORCID http://orcid.org/0000-0002-1788-7571
Chris I R GillNutrition Innovation Centre for Food and Health (NICHE), Ulster University, Coleraine, BT52 1SA, UK. c.gill@ulster.ac.uk.ORCID http://orcid.org/0000-0003-4335-7571
University of Ulster · GB

Funding

Comisión Nacional de Investigación Científica y Tecnológica R15F10005
6 · The paper itself

Abstract

purposeTo investigate the effect of consuming quinoa biscuits on markers of CVD risk over 4 weeks in free-living older adults.

methodsA randomized-controlled, double-blind crossover trial was conducted in which consenting healthy adults aged 50-75 years (n = 40) consumed 15 g quinoa biscuits (60 g quinoa flour/100 g) or control iso-energetic biscuits (made using wheat flour) daily for 28 consecutive days (4 weeks), in addition to their normal diet. Following a 6-week washout, participants consumed the alternate biscuit for a final 4 weeks. Anthropometry and fasted blood samples were obtained before and after each intervention period.

resultsAt the beginning of the trial, mean ± SD total cholesterol concentrations were 6.02 ± 1.22 mmol/L (3.7-9.2 mmol/L); 33 participants (82.5%) had high cholesterol (> 5 mmol/L). No participants were lost to follow-up and there were no changes in habitual dietary intakes or levels of physical activity between each 4-week intervention period. Significantly greater decreases in total and LDL cholesterol concentrations (- 0.30 ± 0.58 and - 0.25 ± 0.38 mmol/L, respectively), TC: HDL ratio (- 0.11 ± 0.30), weight (- 0.61 ± 0.89 kg) and BMI (- 0.22 ± 0.34 kg/m

conclusionConsumption of novel quinoa biscuits produced small, but favorable changes in body weight, BMI, and circulating cholesterol concentrations, all of which may contribute to lowered CVD risk in older adults.

Indexed as

Chenopodium quinoaDietAgedBiomarkersCardiovascular DiseasesCholesterol, HDLC-Reactive ProteinCross-Over StudiesDisease SusceptibilityFatty Acids, UnsaturatedFemaleFlourHumansMaleMiddle AgedTriglyceridesBiomarkersCholesterol, HDLC-Reactive ProteinFatty Acids, UnsaturatedTriglyceridesCardiovascular diseaseCholesterolFatty acidsPUFAQuinoaRandomized controlled trial

Identifiers

PMID31919583
OpenAlexW2999044182

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.