Evidence map›Paper›PMID 31919465›Full record

ArticleScientific reports2020

Mass Spectrometry Imaging of atherosclerosis-affine Gadofluorine following Magnetic Resonance Imaging.

Fabian Lohöfer, Rebecca Buchholz, Almut Glinzer, Katharina Huber, Helena Haas, Georgios Kaissis, Annette Feuchtinger, Michaela Aichler, Peter B Sporns, Carsten Höltke and 9 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 3 countries.

Fabian LohöferDepartment of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Rebecca BuchholzDepartment for Analytical Chemistry, Westfälische Wilhelms-Universität, Münster, Germany.
Almut GlinzerDepartment of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Katharina HuberResearch Unit Analytical Pathology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
Helena HaasDepartment of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Georgios KaissisDepartment of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Annette FeuchtingerResearch Unit Analytical Pathology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
Michaela AichlerResearch Unit Analytical Pathology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
Peter B SpornsTranslational Research Imaging Center, Department of Clinical Radiology, Westfälische Wilhelms-Universität, Münster, Germany.
Carsten HöltkeTranslational Research Imaging Center, Department of Clinical Radiology, Westfälische Wilhelms-Universität, Münster, Germany.
Miriam StöltingTranslational Research Imaging Center, Department of Clinical Radiology, Westfälische Wilhelms-Universität, Münster, Germany.
Franz SchillingDepartment of Nuclear Medicine, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
René M BotnarSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.ORCID http://orcid.org/0000-0002-9447-4367
Melanie A KimmDepartment of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0001-6833-9738
Cornelius FaberTranslational Research Imaging Center, Department of Clinical Radiology, Westfälische Wilhelms-Universität, Münster, Germany.ORCID http://orcid.org/0000-0001-7683-7710
Axel K WalchResearch Unit Analytical Pathology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
Alma ZerneckeInstitute for Experimental Biomedicine, Universitätsklinikum Würzburg, Würzburg, Germany.
Uwe KarstDepartment for Analytical Chemistry, Westfälische Wilhelms-Universität, Münster, Germany.ORCID http://orcid.org/0000-0002-1774-6787
Moritz WildgruberDepartment of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. moritz.wildgruber@ukmuenster.de.
University of Münster · DETUM Klinikum · DEHelmholtz Zentrum München · DEKing's College London · GBUniversitätsklinikum Würzburg · DE

Funding

British Heart Foundation RG/12/1/29262
6 · The paper itself

Abstract

Molecular imaging of atherosclerosis by Magnetic Resonance Imaging (MRI) has been impaired by a lack of validation of the specific substrate responsible for the molecular imaging signal. We therefore aimed to investigate the additive value of mass spectrometry imaging (MSI) of atherosclerosis-affine Gadofluorine P for molecular MRI of atherosclerotic plaques. Atherosclerotic Ldlr

Indexed as

AnimalsAtherosclerosisContrast MediaCoordination ComplexesFemaleFluorocarbonsMagnetic Resonance ImagingMiceMice, KnockoutMolecular ImagingReceptors, LDLSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationContrast MediaCoordination ComplexesFluorocarbonsgadofluorine PReceptors, LDL

Identifiers

PMID31919465
PMCPMC6952459
OpenAlexW2999950493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.