ArticleScientific reports2020
Aedes aegypti insecticide resistance underlies the success (and failure) of Wolbachia population replacement.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 65 citations in OpenAlex.
- Interactions Between Inbreeding, Fitness and the Bacterial Microbiome inEvolutionary applications · 2026Article
- Wolbachia wMel and wAlbB strains differentially impact the vector competence of Aedes aegypti with a Brazilian genetic background for DENV-1 virus.Parasites & vectors · 2026Article
- Blood feeding, microbiota, and layered mosquito immunity: from pathway phenotypes to vector competence.Frontiers in immunology · 2026Review
- Multi-omics insights into mosquito insecticide resistance for integrated vector management.PeerJ · 2026Review
- A Brief History of the Use of Insecticides in Brazil to Control Vector-Borne Diseases, and Implications for Insecticide Resistance.Tropical medicine and infectious disease · 2025Review
- Detection and genetic diversity of Wolbachia and its associated prophage WO in mosquito populations from Ethiopia.Scientific reports · 2025Article
- Ecological dynamics of field Aedes albopictus populations under Wolbachia-mediated suppression.Infectious diseases of poverty · 2025Article
- The long-term persistence of the wMel strain in Rio de Janeiro is threatened by poor integrated vector management and bacterium fitness cost on Aedes aegypti.PLoS neglected tropical diseases · 2025Article
- Strengthening resilience to emerging vector-borne diseases in Europe: lessons learnt from countries facing endemic transmission.The Lancet regional health. Europe · 2025Review
- What is the optimal In2Care stations density to achieve Aedes aegypti population reduction in a dengue endemic setting?PLoS neglected tropical diseases · 2025Article
- Review
- Fitness compatibility and dengue virus Inhibition in a Bangladeshi strain of Aedes aegypti infected with the Wolbachia strain wAlbB.Scientific reports · 2025Article
- UnveilingFrontiers in cellular and infection microbiology · 2025Article
- Review
- Post-release monitoring pathway for the deployment of gene drive-modified mosquitoes for malaria control in Africa.Malaria journal · 2024Article
- Global, asynchronous partial sweeps at multiple insecticide resistance genes in Aedes mosquitoes.Nature communications · 2024Article
- Article
- DENV-1 Titer Impacts Viral Blocking inViruses · 2024Article
- Evaluation of the biological efficacy and susceptibility in Aedes aegypti to the pyrethroid insecticides deltamethrin and cyfluthrin during the Zika virus outbreak in Kuna Yala, PanamaBiomedica : revista del Instituto Nacional de Salud · 2023Article
- Dengue Exposure andViruses · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquitoes that carry Wolbachia endosymbionts may help control the spread of arboviral diseases, such as dengue, Zika and chikungunya. Wolbachia frequencies systematically increase only when the frequency-dependent advantage due to cytoplasmic incompatibility exceeds frequency-independent costs, which may be intrinsic to the Wolbachia and/or can be associated with the genetic background into which Wolbachia are introduced. Costs depend on field conditions such as the environmental pesticide load. Introduced mosquitoes need adequate protection against insecticides to ensure survival after release. We model how insecticide resistance of transinfected mosquitoes determines the success of local Wolbachia introductions and link our theoretical results to field data. Two Ae. aegypti laboratory strains carrying Wolbachia were released in an isolated district of Rio de Janeiro, Brazil: wMelBr (susceptible to pyrethroids) and wMelRio (resistant to pyrethroids). Our models elucidate why releases of the susceptible strain failed to result in Wolbachia establishment, while releases of the resistant strain led to Wolbachia transforming the native Ae. aegypti population. The results highlight the importance of matching insecticide resistance levels in release stocks to those in the target natural populations during Wolbachia deployment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.