Evidence map›Paper›PMID 31919282›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Loss of TSC complex enhances gluconeogenesis via upregulation of

Dritan Liko, Andrzej Rzepiela, Vanja Vukojevic, Mihaela Zavolan, Michael N Hall

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. The mTOR-Autophagy Axis and the Control of Metabolism.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dritan LikoBiozentrum, University of Basel, CH-4056 Basel, Switzerland.
Andrzej RzepielaBiozentrum, University of Basel and Swiss Institute of Bioinformatics, CH-4056 Basel, Switzerland.
Vanja VukojevicDivision of Molecular Neuroscience, Department of Psychology, University of Basel, CH-4055 Basel, Switzerland.
Mihaela ZavolanBiozentrum, University of Basel and Swiss Institute of Bioinformatics, CH-4056 Basel, Switzerland.
Michael N HallBiozentrum, University of Basel, CH-4056 Basel, Switzerland; m.hall@unibas.ch.
University of Basel · CHSIB Swiss Institute of Bioinformatics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loss of the tumor suppressor tuberous sclerosis complex 1 (

Indexed as

Up-RegulationAnimalsCalcium-Binding ProteinsGenetic LociGenomic ImprintingGluconeogenesisIodide PeroxidaseLiverMaleMechanistic Target of Rapamycin Complex 1MiceMice, KnockoutMicroRNAsSequence AnalysisSignal TransductionTranscriptomeCalcium-Binding ProteinsDlk1 protein, mouseIodide Peroxidaseiodothyronine deiodinase type IIIMechanistic Target of Rapamycin Complex 1MicroRNAsTsc1 protein, mouseTuberous Sclerosis Complex 1 ProteinCpG methylationDlk1-Dio3glucose metabolismmiRNAmTOR

Identifiers

PMID31919282
PMCPMC6983401
OpenAlexW3000015426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.