Evidence map›Paper›PMID 31919243›Full record

ArticleRNA (New York, N.Y.)2020

The presence of the ACA box in archaeal H/ACA guide RNAs promotes atypical pseudouridylation.

Mrinmoyee Majumder, Shaoni Mukhopadhyay, Parinati Kharel, Ramesh Gupta

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  2. tRNA pseudouridine synthase D (TruD) fromRNA (New York, N.Y.) · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mrinmoyee MajumderDepartment of Biochemistry and Molecular Biology, Southern Illinois University, Carbondale, Illinois 62901-4413, USA.
Shaoni MukhopadhyayDepartment of Biochemistry and Molecular Biology, Southern Illinois University, Carbondale, Illinois 62901-4413, USA.
Parinati Kharel *Department of Biochemistry and Molecular Biology, Southern Illinois University, Carbondale, Illinois 62901-4413, USA.
Ramesh GuptaDepartment of Biochemistry and Molecular Biology, Southern Illinois University, Carbondale, Illinois 62901-4413, USA.
Southern Illinois University Carbondale · US

Funding

RNA SPLICING IN ARCHAEAR15GM055945 · NIGMS · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI GUPTA, RAMESH · 1998 to 2015
$1.3M
NIGMS NIH HHS R15 GM055945
6 · The paper itself

Abstract

Archaea and eukaryotes, in addition to protein-only enzymes, also possess ribonucleoproteins containing an H/ACA guide RNA plus four proteins that produce pseudouridine (Ψ). Although typical conditions for these RNA-guided reactions are known, certain variant conditions allow pseudouridylation. We used mutants of the two stem-loops of the

Indexed as

RNA Processing, Post-TranscriptionalArchaeal ProteinsHaloferax volcaniiNucleotide MotifsPseudouridineRNA, ArchaealRNA, Guide, CRISPR-Cas SystemsArchaeal ProteinsPseudouridineRNA, ArchaealRNA, Guide, CRISPR-Cas SystemsArchaeaCbf5 proteinHaloferax volcaniipseudouridineribosomal RNARNA modification

Identifiers

PMID31919243
PMCPMC7075261
OpenAlexW3000421028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.