Evidence map›Paper›PMID 31919100›Full record

ArticleThe Journal of biological chemistry2020

A fluorescence-activatable reporter of flavivirus NS2B-NS3 protease activity enables live imaging of infection in single cells and viral plaques.

Jorge L Arias-Arias, Derek J MacPherson, Maureen E Hill, Jeanne A Hardy, Rodrigo Mora-Rodríguez

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The Virus-Induced Cytopathic Effect.Sub-cellular biochemistry · 2023
    Article
  6. Protein Abundance of Drug Transporters in Human Hepatitis C Livers.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Dual-fluorescent reporter for live-cell imaging of the ER during DENV infection.Frontiers in cellular and infection microbiology · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jorge L Arias-AriasCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José 11501-2060, Costa Rica.
Derek J MacPhersonDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003.
Maureen E HillDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003.
Jeanne A HardyDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003.
Rodrigo Mora-RodríguezCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José 11501-2060, Costa Rica. Electronic address: rodrigo.morarodriguez@ucr.ac.cr.
University of Massachusetts Amherst · USUniversidad de Costa Rica · CR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genus

Indexed as

Genes, ReporterAnimalsCell DeathCell LineDengue VirusFlavivirusFlavivirus InfectionsFluorescenceGreen Fluorescent ProteinsHumansKineticsSignal-To-Noise RatioViral Nonstructural ProteinsZika VirusGreen Fluorescent ProteinsViral Nonstructural Proteinscell-based reportercell deathdengue virus (DENV)flavivirusfluorescenceinternal cleavageNS2B–NS3plaque assayproteaseZika virus (ZIKV)

Identifiers

PMID31919100
PMCPMC7039541
OpenAlexW2999928311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.