Evidence map›Paper›PMID 31918705›Full record

ArticleJournal of translational medicine2020

Cocaine and amphetamine-regulated transcript prepropeptide gene (CARTPT) polymorphism interacts with Diet Quality Index-International (DQI-I) and Healthy Eating Index (HEI) to affect hypothalamic hormones and cardio-metabolic risk factors among obese individuals.

Mahsa Mahmoudi-Nezhad, Mahdieh Abbasalizad Farhangi, Houman Kahroba

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mahsa Mahmoudi-NezhadNutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mahdieh Abbasalizad FarhangiDrug Applied Research Center, Tabriz University of Medical Sciences, Attar-Neishabouri Ave, Golgasht St, Tabriz, 5165665931, Iran. abbasalizad_m@yahoo.com.
Houman KahrobaMolecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Tabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiologic studies show that cocaine- and amphetamine-regulated transcript prepropeptide (CARTPT) gene polymorphism modifies diet-obesity relationships. However, the interaction between CARTPT gene polymorphism and diet quality indices have not been investigated yet. The current study was aimed to evaluate the interaction between major dietary indices including Diet Quality Index-International (DQI-I) and Healthy Eating Index (HEI)-2015 and CARTPT gene rs2239670 variants among apparently healthy obese Iranians.

methodsThis cross-sectional study was carried out by employing 288 apparently healthy obese adults aged 20-50 years with a BMI of 30-40 kg/m

resultsThe significant interactions were identified between CARTPT gene polymorphism and HEI, affecting BMR (P

conclusionCurrent study showed the effects of interaction between CARTPT genotype with adherence to HEI and DQI-I scores on obesity-related anthropometric and metabolic risk-factors.

Indexed as

DietDiet, HealthyHeart Disease Risk FactorsAdultBody Mass IndexCocaine- and Amphetamine-Regulated Transcript ProteinCross-Sectional StudiesHormonesHumansHypothalamusIranMiddle AgedNerve Tissue ProteinsObesityPolymorphism, GeneticRisk FactorsCocaine- and Amphetamine-Regulated Transcript ProteinHormonesNerve Tissue ProteinsAgRPCARTPTDiet qualityGene-diet interactionMetabolic risk factorsObesityα-MSH

Identifiers

PMID31918705
PMCPMC6953221
OpenAlexW3011672844

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.