Evidence map›Paper›PMID 31918662›Full record

ArticleBMC cardiovascular disorders2020

Platelet to lymphocyte ratio predicting 6-month primary patency of drug-coated balloon for femoropopliteal disease.

Yanhua Zhen, Zhihui Chang, Zhaoyu Liu, Jiahe Zheng

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yanhua ZhenDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, 36, Sanhao Street, Heping District, Shenyang City, China.
Zhihui ChangDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, 36, Sanhao Street, Heping District, Shenyang City, China.
Zhaoyu LiuDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, 36, Sanhao Street, Heping District, Shenyang City, China.
Jiahe ZhengDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, 36, Sanhao Street, Heping District, Shenyang City, China. zhengjh120624@126.com.ORCID 0000-0003-2057-4776

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory reaction is an essential factor in the occurrence, development and prognosis of femoropopliteal disease (FPD). The ratio of platelets to lymphocytes (PLR) is a new indicator reflecting platelet aggregation and burden of systemic inflammation. Our study is to explore the association between preoperative platelet-to-lymphocyte ratio (pre-PLR) and 6-month primary patency (PP) after drug-coated balloon (DCB) in FPD.

methodsThere were 70 patients who underwent DCB for FPD contained in the study. According to 6-month PP, patients were divided into group A (PP ≥6 months, n = 54) and group B (PP < 6 months, n = 16). Logistic regression analysis was used to identify potential predictors for 6-month PP after DCB in FPD. A receiver operating characteristic (ROC) curve analysis was used to identify the cut-off value of pre-PLR to predict 6-month PP.

resultsLogistic regression analysis showed that pre-PLR (OR: 1.008, 95% CI: 1.001-1.016, P = 0.031) and lesion length > 10 cm (OR: 4.305, 95% CI: 1.061-17.465, P = 0.041) were independently predictive for 6-month PP. The cutoff value of pre-PLR obtained from the ROC analysis was 127.35 to determine 6-month PP with the area of 0.839. Subgroup analysis was conducted based on the cutoff value of pre-PLR. The 6-month PP in the group of pre-PLR < 127.35 was higher than that of pre-PLR ≥ 127.35 group (p < 0.001).

conclusionsThe present study indicated that an elevated pre-PLR was an effective additional indicator for predicting early PP in FPD after DCB.

Indexed as

Blood PlateletsCoated Materials, BiocompatibleLymphocytesVascular PatencyAgedAngioplasty, BalloonCardiovascular AgentsFemaleFemoral ArteryHumansLymphocyte CountMaleMiddle AgedPeripheral Arterial DiseasePlatelet CountPopliteal ArteryCardiovascular AgentsCoated Materials, BiocompatibleDrug-coated balloonFemoropopliteal diseaseLymphocytePlateletPrimary patency

Identifiers

PMID31918662
PMCPMC6950933

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.