Evidence map›Paper›PMID 31918657›Full record

ArticleBMC emergency medicine2020

Do Bacteremic patients with end-stage renal disease have a fever when presenting to the emergency department? A paired, retrospective cohort study.

Sarah L Weatherall, Alison B Chambers, Leonard A Mermel

Abstract read
In one paragraph

Article in BMC emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sarah L WeatherallWarren Alpert Medical School of Brown University, Providence, RI, USA.
Alison B ChambersDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Leonard A MermelDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA. lmermel@lifespan.org.ORCID 0000-0002-8898-7406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFever is a common symptom when patients present to Emergency Departments. It is unclear if the febrile response of bacteremic hemodialysis-dependent patients differs from bacteremic patients not receiving hemodialysis. The objective of this study was to compare Emergency Departments triage temperatures of patients with and without hemodialysis-dependent end-stage rental disease who have Staphylococcus aureus bacteremia and determine the incidence of afebrile S. aureus bacteremia.

methodsPaired, retrospective cohort study of 37 patients with and 37 patients without hemodialysis hospitalized with Methicillin-resistant or Methicillin-susceptible S. aureus bacteremia. Emergency Department triage temperatures were reviewed for all patients, as were potential confounding variables.

results54% (95% CI, 38-70%) and 82% (95% CI 65-91%) of hemodialysis and non-hemodialysis patients did not have a detectable fever (<100.4 °F) at triage. Triage temperatures were 100.5 °F (95% CI 99.9-101.2 °F) and 99.0 °F (95% CI 98.4-99.6 °F) in the hemodialysis and non-hemodialysis cohorts, respectively (p < 0.001). Triage temperature in patients with and without diabetes mellitus was 99.2 °F (95% CI 98.4-99.9 °F) and 100.4 °F (95% CI 99.7-101.0 °F), respectively (p = 0.03). We were unable to detect a significant effect of diabetes mellitus and other potential confounding variables on differences in temperature between the hemodialysis and non-hemodialysis cohorts (all interactions p > 0.19).

conclusionsHemodialysis-dependent patients with S. aureus bacteremia had significantly higher temperatures than non- hemodialysis-dependent end stage renal disease patients but more than half of patients were without detectable fever at triage, possibly reflecting use of insensitive methods for measuring temperature. Absence of fever at presentation to the Emergency Department should not delay blood culture acquisition in patients who are at increased risk of S. aureus bacteremia.

Indexed as

AdultAgedAged, 80 and overBacteremiaDiabetes MellitusEmergency Service, HospitalFemaleFeverHumansKidney Failure, ChronicMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedRenal DialysisRetrospective StudiesStaphylococcal InfectionsBacteremiaEnd-stage renal diseaseFeverHemodialysisStaphylococcus aureus

Identifiers

PMID31918657
PMCPMC6953182

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.