Evidence map›Paper›PMID 31918559›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Effect of Weight Loss on Upper Airway Anatomy and the Apnea-Hypopnea Index. The Importance of Tongue Fat.

Stephen H Wang, Brendan T Keenan, Andrew Wiemken, Yinyin Zang, Bethany Staley, David B Sarwer, Drew A Torigian, Noel Williams, Allan I Pack, Richard J Schwab

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 118 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 5 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05311280 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of High Intensity Interval Exercise and Myofunctional Therapy on Obstructive Sleep Apnea: a Randomized Clinical Controlled Trial

TypeinterventionalSponsorTaoyuan General HospitalRan2022 to 2022Enrolled40ConditionsObstructive Sleep ApneaArmshigh intensity interval training plus myotherapy, home exercise plus myotherapy
NCT06949969 nacompletednot on this mapstarted 2025, after this paper: background citation

Alesis OSA-1 Double-Blinded Randomized Study of Obstructive Sleep Apnea Treatment Using A Patented Noncoherent Medical Light

TypeinterventionalSponsorPhotonica USA, LLCRan2025 to 2025Enrolled35ConditionsObstructive Sleep ApneaArmsOSA LLLT treatment device, Sham Comparator
3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 5 syntheses or guidelines pooled it, 205 citations in OpenAlex.

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  12. From coexistence to causation: defining adiposity-attributable obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  13. Article
  14. Sleep and obesity-known interactions and open questions.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Review
  15. Review
  16. Article
  17. Airway Anatomy and Surgical Management in Obstructive Sleep Apnea.Clinical and experimental otorhinolaryngology · 2026
    Review
  18. Review
  19. Article
  20. Article

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Stephen H WangAlbert Einstein College of Medicine, Bronx, New York.
Brendan T KeenanCenter for Sleep and Circadian Neurobiology.
Andrew WiemkenCenter for Sleep and Circadian Neurobiology.
Yinyin ZangCenter for Sleep and Circadian Neurobiology.
Bethany StaleyCenter for Sleep and Circadian Neurobiology.
David B SarwerCenter for Obesity Research and Education at the College of Public Health at Temple University, Philadelphia, Pennsylvania.
Drew A TorigianDepartment of Radiology.
Noel WilliamsDepartment of Surgery, and.
Allan I PackCenter for Sleep and Circadian Neurobiology.
Richard J SchwabCenter for Sleep and Circadian Neurobiology.
Canadian Sleep & Circadian Network · CAAlbert Einstein College of Medicine · USTemple University · US

Funding

Understanding the relationship between obesity and tongue fat in humans and ratsP01HL094307 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PACK, ALLAN I · 2009 to 2020
$23.7M
Obesity & OSA: Understanding the Importance of Tongue Fat and Metabolic FunctionR01HL089447 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI SCHWAB, RICHARD J. · 2008 to 2011
$2.4M
NHLBI NIH HHS P01 HL094307NHLBI NIH HHS R01 HL089447
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultFemaleHumansMaleMiddle AgedObesitySleep Apnea, ObstructiveTongueUnited StatesWeight Lossapnea–hypopnea indexobstructive sleep apneaupper airwayweight loss

Identifiers

PMID31918559
PMCPMC7068828
OpenAlexW2999098554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.