Evidence map›Paper›PMID 31918362›Full record

ArticleAnaerobe2020

Inhibition of Bacteroidetes and Firmicutes by select phytochemicals.

Jourdan E Lakes, Christopher I Richards, Michael D Flythe

Open access · greenAbstract read
In one paragraph

Article in Anaerobe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Biological Mechanisms of Polyphenols againstInfectious disorders drug targets · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. The New Antibacterial Properties of the Plants:Frontiers in microbiology · 2021
    Review
  13. Article
  14. Capsaicin and Gut Microbiota in Health and Disease.Molecules (Basel, Switzerland) · 2020
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jourdan E LakesDepartment of Chemistry, College of Arts & Sciences, University of Kentucky, Lexington, KY, USA.
Christopher I RichardsDepartment of Chemistry, College of Arts & Sciences, University of Kentucky, Lexington, KY, USA.
Michael D FlytheUSDA Agricultural Research Service Forage-Animal Production Research Unit, Lexington, KY, USA; Department of Animal and Food Sciences, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY, USA. Electronic address: michael.flythe@usda.gov.
University of Kentucky · USAgricultural Research Service · US

Funding

Training in Drug Abuse Related Research.T32DA016176 · NIDA · UNIVERSITY OF KENTUCKY · PI DWOSKIN, LINDA P · 2004 to 2020
$4.0M
NIDA NIH HHS T32 DA016176
6 · The paper itself

Abstract

Current research indicates that changes in gut microbiota can impact the host, but it is not always clear how dietary and environmental factors alter gut microbiota. One potential factor is antimicrobial activity of compounds ingested by the host. The goal of this study was to determine the antimicrobial activity of common plant secondary metabolites against pure cultures of paired, structurally and phylogenetically distinct gastrointestinal bacteria of human or bovine origin: Prevotella bryantii B

Indexed as

AlkaloidsAnti-Bacterial AgentsBacillotaBacteroidetesGastrointestinal MicrobiomeHumansMicrobial Sensitivity TestsPhytochemicalsAlkaloidsAnti-Bacterial AgentsPhytochemicalsAlkaloidsAntimicrobial activityBacteroides fragilisClostridioides difficileInhibitory concentrationNicotine

Identifiers

PMID31918362
PMCPMC7441489
OpenAlexW2998517479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.