Evidence map›Paper›PMID 31918232›Full record

Trial reportDrug and alcohol dependence2020

The relationship between perceived stress and depression in substance use disorder treatment.

R Kathryn McHugh, Dawn E Sugarman, Laurel Meyer, Garrett M Fitzmaurice, Shelly F Greenfield

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

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  6. The phenotype of recovery XI: associations of sleep quality and perceived stress with discounting and quality of life in substance use recovery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

R Kathryn McHughMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. Electronic address: kmchugh@mclean.harvard.edu.
Dawn E SugarmanMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.
Laurel MeyerMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA.
Garrett M FitzmauriceMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.
Shelly F GreenfieldMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.
Harvard University · USMcLean Hospital · US

Funding

Recovery Group for Women with Substance Use DisordersR01DA015434 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI GREENFIELD, SHELLY F. · 2002 to 2011
$3.1M
Mentoring in Substance Abuse Treatment ResearchK24DA019855 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI GREENFIELD, SHELLY F. · 2005 to 2014
$1.8M
GENDER DIFFERENCES IN MECHANISMS OF RECOVERY FROM OPIOID USE DISORDER AND ANXIETYK23DA035297 · NIDA · MCLEAN HOSPITAL · PI MCHUGH, REBECCA KATHRYN · 2014 to 2018
$959k
NIDA NIH HHS K23 DA035297NIDA NIH HHS K24 DA019855NIDA NIH HHS R01 DA015434
6 · The paper itself

Abstract

backgroundDepression is highly prevalent among individuals with substance use disorders (SUDs), especially women, and has been noted to improve during SUD treatment. Perceived stress is independently related to severity of depression and substance use disorders (SUDs) as well as recurrence of symptoms and relapse following treatment. The aim of this study was to investigate among adults enrolled in SUD treatment whether levels of perceived stress and substance use over the course of treatment were related to reduction in depression.

methodsThis is a secondary analysis of data from the Women's Recovery Group Study. Women (n = 100) were randomized to either single- or mixed-gender group therapy and men (n = 58) received mixed-gender group therapy. Measures of substance use, perceived stress and depressive symptoms were collected for 6 months following treatment completion. In this study, we used lagged mixed models to investigate whether levels of substance use and perceived stress at each time point were associated with changes in depression at the subsequent time point.

resultsResults indicated that depressive symptoms significantly improved over time. Both substance use and perceived stress were associated with subsequent depressive symptoms. Importantly, stress was associated with symptoms when controlling for substance use, suggesting that changes in depressive symptoms were not solely attributable to levels of substance use.

conclusionsThese results suggest that both stress and substance use are associated with improvements in depressive symptoms in substance use disorder treatment. Although preliminary, these results provide further support for the importance of targeting stress reduction in people with substance use disorders.

Indexed as

Sex FactorsAdultDepressionFemaleHumansMaleMiddle AgedPsychotherapy, GroupRecurrenceStress, PsychologicalSubstance-Related DisordersTreatment OutcomeDepressionGenderStressSubstance use disorder

Identifiers

PMID31918232
PMCPMC7071730
OpenAlexW2996809276

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.