Evidence map›Paper›PMID 31918227›Full record

ReviewBiomaterials2020

Microneedles for transdermal diagnostics: Recent advances and new horizons.

Gui-Shi Liu, Yifei Kong, Yensheng Wang, Yunhan Luo, Xudong Fan, Xi Xie, Bo-Ru Yang, Mei X Wu

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 223 citations in OpenAlex.

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  19. Microneedle Sensors for Point-of-Care Diagnostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  20. Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Gui-Shi LiuGuangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, College of Science & Engineering, Jinan University, Guangzhou, 510632, China.
Yifei KongWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Yensheng WangWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Yunhan LuoGuangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, College of Science & Engineering, Jinan University, Guangzhou, 510632, China.
Xudong FanDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Xi XieState Key Laboratory of Optoelectronic Materials and Technologies, School of Electronics and Information Technology, Sun Yat-Sen University, Guangzhou, 510006, China. Electronic address: xiexi27@mail.sysu.edu.cn.
Bo-Ru YangState Key Laboratory of Optoelectronic Materials and Technologies, School of Electronics and Information Technology, Sun Yat-Sen University, Guangzhou, 510006, China. Electronic address: paulyang68@icloud.com.
Mei X WuWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA. Electronic address: MWU5@mgh.harvard.edu.
Harvard University · USJinan University · CNSun Yat-sen University · CNMassachusetts General Hospital · USUniversity of Michigan–Ann Arbor · US

Funding

Laser-facilitated powder-allergen delivery for epicutaneous immunotherapyR21AI113458 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI WU, MEI X · 2014 to 2015
$465k
NIAID NIH HHS R21 AI113458
6 · The paper itself

Abstract

Point-of-care testing (POCT), defined as the test performed at or near a patient, has been evolving into a complement to conventional laboratory diagnosis by continually providing portable, cost-effective, and easy-to-use measurement tools. Among them, microneedle-based POCT devices have gained increasing attention from researchers due to the glorious potential for detecting various analytes in a minimally invasive manner. More recently, a novel synergism between microneedle and wearable technologies is expanding their detection capabilities. Herein, we provide an overview on the progress in microneedle-based transdermal biosensors. It covers all the main aspects of the field, including design philosophy, material selection, and working mechanisms as well as the utility of the devices. We also discuss lessons from the past, challenges of the present, and visions for the future on translation of these state-of-the-art technologies from the bench to the bedside.

Indexed as

Biosensing TechniquesWearable Electronic DevicesAdministration, CutaneousDrug Delivery SystemsHumansNeedlesContinuous monitoringHome-based diagnosisMicroneedleMinimally invasivePoint-of-careWearable or portable biosensors

Identifiers

PMID31918227
PMCPMC7432994
OpenAlexW2997719832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.