Evidence map›Paper›PMID 31917748›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2020

Brief Report: Accuracy in Self-Report of Viral Suppression Among HIV-Positive Men With HIV-Negative Male Partners.

Rob Stephenson, Anna Bratcher, Matthew J Mimiaga, Robert Garofalo, Marco A Hidalgo, Samuel Hoehnle, Patrick S Sullivan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rob StephensonDepartment of Systems, Population and Leadership, The Center for Sexuality and Health Disparities, School of Nursing, University of Michigan, Ann Arbor, MI.
Anna BratcherDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA.
Matthew J MimiagaCenter for Health Equity Research, School of Public Health, Brown University, Providence, RI.
Robert GarofaloAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Marco A HidalgoDivision of Adolescent and Young Adult Medicine, Children's Hospital Los Angeles, Los Angeles, CA.
Samuel HoehnleAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Patrick S SullivanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.

Funding

Study of Hearing and Balance in Middle Aged and Aging Men and Women in the MACS-WIHS Combined Cohort StudyU01HL146333 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Roger Detels, Matthew James Mimiaga · 2019 to 2026
$32.2M
CVCTPlus: A Couples-Based Approach to Linkage to Care and ARV AdherenceR01HD075655 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAROFALO, ROBERT, MIMIAGA, MATTHEW JAMES · 2013 to 2017
$2.9M
NHLBI NIH HHS U01 HL146333NICHD NIH HHS R01 HD075655
6 · The paper itself

Abstract

backgroundAmong men who have sex with men, there is now clear evidence that the risk of HIV transmission through condomless sex when the HIV-positive partner is virally suppressed is effectively zero. However, an understanding of the accuracy of reporting of viral load among serodiscordant same-sex male couples is missing from the literature.

settingThis analysis uses data from the baseline sample of Stronger Together, a randomized controlled efficacy trial of an innovative dyadic intervention to enhance antiretroviral therapy adherence for HIV serodiscordant male couples in 3 US cities (Atlanta, Boston, and Chicago).

methodsBiomarker-confirmed and self-reported measures of viral load were used to assess the accuracy of self-report of viral suppression. In this descriptive analysis, the percentage of men who inaccurately reported being virally suppressed is compared across demographic, relationship, and HIV care characteristics.

resultsResults confirm those of other recent studies that have shown relatively high levels of inaccuracy in reporting of viral suppression. Although 72.5% of men could accurately report their viral load status, 20% reported that they were virally suppressed when they did not have a biomarker-confirmed measure of viral suppression.

conclusionThese results highlight the need to provide interventions to men who have sex with men living with HIV to support access to care and ensure current knowledge of viral load and to continue to support primary prevention of HIV through condom use and pre-exposure prophylaxis. For couples, particularly serodiscordant male couples, interventions that can teach the couple how to collaborate to achieve and maintain viral suppression for the positive partner are an urgent and pragmatic programmatic priority that can equip couples with the knowledge required to correctly implement U = U strategies.

Indexed as

Homosexuality, MaleSelf ReportAdultAgedAnti-HIV AgentsBiomarkersCondomsFemaleHIV InfectionsHumansMaleMiddle AgedPre-Exposure ProphylaxisSafe SexViral LoadYoung AdultAnti-HIV AgentsBiomarkers

Identifiers

PMID31917748
PMCPMC8754005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.