Evidence map›Paper›PMID 31917152›Full record

ArticleNeuropharmacology2020

Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species.

Adam L Halberstadt, Muhammad Chatha, Adam K Klein, Jason Wallach, Simon D Brandt

Open access · greenAbstract read
In one paragraph

Article in Neuropharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 259 citations in OpenAlex.

  1. Psilocybin produces amplified acute responses and sex-specific long-term increases in sensorimotor gating in the mGlu5 knockout mouse model of schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  2. Deconstruction of lysergic acid diethylamide.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
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  5. Review
  6. Review
  7. Article
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  10. Psychedelics produce enduring enhancement of reward responsiveness in male rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  11. Article
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  14. Review
  15. Article
  16. Review
  17. Article
  18. ACS omega · 2026
    Article
  19. Stereoselective, sex-dependent 5-HTNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  20. Article

103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Adam L HalberstadtDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA; Research Service, VA San Diego Healthcare System, San Diego, CA, USA. Electronic address: ahalberstadt@ucsd.edu.
Muhammad ChathaDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Adam K KleinDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Jason WallachDepartment of Pharmaceutical Sciences, University of the Sciences, Philadelphia, PA, USA; Substance Use Disorders Institute, University of the Sciences, Philadelphia, PA, USA.
Simon D BrandtSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
University of California, San Diego · USLiverpool John Moores University · GBUniversity of the Sciences · US

Funding

Fellowship on Biological Psychiatry and NeuroscienceT32MH018399 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pei-an (Betty) Shih · 1986 to 2026
$7.3M
The Next Generation of Hallucinogens: A New Class of Synthetic Psychoactive DrugsR01DA041336 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALBERSTADT, ADAM L. · 2017 to 2020
$1.4M
NIDA NIH HHS R01 DA041336NIMH NIH HHS T32 MH018399
6 · The paper itself

Abstract

Serotonergic hallucinogens such as lysergic acid diethylamide (LSD) induce head twitches in rodents via 5-HT

Indexed as

AnimalsDiscrimination LearningDose-Response Relationship, DrugHallucinogensHead MovementsHumansMagnetometryMaleMiceMice, Inbred C57BLRatsReceptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor AgonistsSpecies SpecificityHallucinogensReceptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor AgonistsBehavioral modelDMTDOMHead shakeMescalineNBOMeN,N-dimethyltryptaminePsilocybinPsychedelic

Identifiers

PMID31917152
PMCPMC9191653
OpenAlexW2999364864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.