Evidence map›Paper›PMID 31916935›Full record

ArticleeLife2020

Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification.

Parisa Asghari, David Rl Scriven, Myles Ng, Pankaj Panwar, Keng C Chou, Filip van Petegem, Edwin Dw Moore

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Cylindrical Crystallization of CaInternational journal of molecular sciences · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Growth-Associated Protein-43 Loss Promotes CaAntioxidants (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Nanoscale organization of cardiac calcium channels is dependent on thyroid hormone status.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  13. Article
  14. Article
  15. Propagation of conformational instability in FK506-binding protein FKBP12.Biochimica et biophysica acta. Proteins and proteomics · 2024
    Article
  16. Article
  17. RyR2 phosphorylation alters dyad architecture.The Journal of general physiology · 2024
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Parisa AsghariDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.ORCID 0000-0003-2285-3242
David Rl ScrivenDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.ORCID 0000-0003-1828-1405
Myles NgDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Pankaj PanwarDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada.
Keng C ChouDepartment of Chemistry, University of British Columbia, Vancouver, Canada.
Filip van PetegemDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada.ORCID 0000-0003-2728-8537
Edwin Dw MooreDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.ORCID 0000-0001-7519-5592
University of British Columbia · CA

Funding

CIHR 148527CIHR PJT-153305
6 · The paper itself

Abstract

The effects of the immunophilins, FKBP12 and FKBP12.6, and phosphorylation on type II ryanodine receptor (RyR2) arrangement and function were examined using correlation microscopy (line scan confocal imaging of Ca

Indexed as

Protein Processing, Post-TranslationalAnimalsCalciumHeart VentriclesMyocytes, CardiacPhosphorylationProtein Structure, QuaternaryRatsRats, WistarRyanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumTacrolimus Binding Protein 1ATacrolimus Binding ProteinsCalciumRyanodine Receptor Calcium Release ChannelRyR2 protein, ratTacrolimus Binding Protein 1Atacrolimus binding protein 1BTacrolimus Binding Proteins3D electron tomographycell biologyexcitation-contraction couplingimmunophilinsratryanodine receptorsuperresolution microscopy

Identifiers

PMID31916935
PMCPMC6994221
OpenAlexW2999699470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.