Observational studyAmerican journal of respiratory and critical care medicine2020
PERSEVERE Biomarkers Predict Severe Acute Kidney Injury and Renal Recovery in Pediatric Septic Shock.
Open access · greenAbstract readObservational Study
In one paragraph
Observational study in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Diagnostic accuracy of renal angina index alone or in combination with biomarkers for predicting acute kidney injury in children.Pediatric nephrology (Berlin, Germany) · 2022Pooled it
- Development and validation of prediction models for any and severe acute kidney injury in children with sepsis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Short-Chain Fatty Acids in Sepsis: Mechanisms of Action and Therapeutic Advances.Biomedicines · 2026Review
- Pediatric sepsis-associated acute kidney injury: leveraging pathophysiology for risk stratification and identification of treatable traits.Pediatric nephrology (Berlin, Germany) · 2026Review
- External Validation, Molecular Signatures, and Therapeutic Relevance of Pediatric Sepsis-Associated Acute Kidney Injury Subphenotypes.Critical care medicine · 2026Observational
- Serum metabolomic profile in children with sepsis-associated acute kidney injury.Clinical and experimental pediatrics · 2026Article
- Pathophysiology and Management of Sepsis-associated Acute Kidney Injury.Clinics in chest medicine · 2026Review
- Multi-omic and computational approaches for biomarker discovery and clinical translation in pediatric sepsis.Frontiers in pharmacology · 2026Review
- Risk factors for predicting acute kidney injury in children with septic shock: a retrospective cohort study.Pediatric nephrology (Berlin, Germany) · 2025Article
- The Clinical View of Sepsis-Associated AKI: How Basic Science Can Help Solve This Problem.Seminars in nephrology · 2025Review
- Research Progress on Signalling Pathways Related to Sepsis-Associated Acute Kidney Injury in Children.Current issues in molecular biology · 2025Review
- Modification of the Cardiac Renal Angina Index for Predicting Adverse Kidney Events After Pediatric Cardiac Surgery.Journal of the American Heart Association · 2025Observational
- Potential biomarkers used for risk estimation of pediatric sepsis-associated organ dysfunction and immune dysregulation.Pediatric research · 2025Review
- The challenges for developing prognostic prediction models for acute kidney injury in hospitalized children: A systematic review.Pediatric investigation · 2025Review
- The authors reply.Critical care medicine · 2025Article
- Advances and Challenges in Pediatric Sepsis Diagnosis: Integrating Early Warning Scores and Biomarkers for Improved Prognosis.Biomolecules · 2025Review
- The promise of biomarkers: precision medicine will pave a roadmap for pediatric acute kidney injury management in critically ill children.Intensive care medicine. Paediatric and neonatal · 2025Review
- Utility of plasma suPAR to identify AKI and sepsis associated AKI in critically ill children.iScience · 2024Article
- Revisiting Post-ICU Admission Fluid Balance Across Pediatric Sepsis Mortality Risk Strata: A Secondary Analysis of a Prospective Observational Cohort Study.Critical care explorations · 2024Article
- Precision management of acute kidney injury in the intensive care unit: current state of the art.Intensive care medicine · 2023Review
Corrections and comments
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Authors and funding
17 authors at 15 institutions in 1 country.
Natalja L StanskiCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0003-4473-8376
Erin K StensonChildren's Hospital Colorado, Aurora, Colorado.
Natalie Z CvijanovichUniversity of California San Francisco Benioff Children's Hospital Oakland, Oakland, California.
Scott L WeissChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Julie C FitzgeraldChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Michael T BighamAkron Children's Hospital, Akron, Ohio.
Parag N JainTexas Children's Hospital and Baylor College of Medicine, Houston, Texas.
Adam SchwarzChildren's Hospital of Orange County, Orange, California.
Riad LutfiRiley Hospital for Children, Indianapolis, Indiana.
Jeffrey NowakChildren's Hospital and Clinics of Minnesota, Minneapolis, Minnesota.
Geoffrey L AllenChildren's Mercy Hospital, Kansas City, Missouri.
Neal J ThomasPenn State Hershey Children's Hospital, Hershey, Pennsylvania.
Jocelyn R GrunwellChildren's Healthcare of Atlanta at Eggleston, Atlanta, Georgia.
Torrey BainesUniversity of Florida Health, Gainesville, Florida.
Michael QuasneyC.S. Mott Children's Hospital at the University of Michigan, Ann Arbor, Michigan.
Bereketeab HaileselassieLucile Packard Children's Hospital Stanford, Palo Alto, California; and.
Hector R WongCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0001-7989-1173
Children's Hospital of Philadelphia · USCincinnati Children's Hospital Medical Center · USAkron Children's Hospital · USBaylor College of Medicine · USChildren's Healthcare of Atlanta · USChildren's Hospital Colorado · USChildren's Hospital of Orange County · USChildren's Mercy Hospital · USChildren's Minnesota · USLucile Packard Children's Hospital · USPenn State Milton S. Hershey Medical Center · USRiley Hospital for Children · USUniversity of California, San Francisco · USUniversity of Florida Health · USUniversity of Michigan · US
Funding
Supplement for MIRA award_Wong_2021R35GM126943 · NIGMS · CINCINNATI CHILDRENS HOSP MED CTR · PI ALDER, MATTHEW N · 2018 to 2022
$2.7MPediatric septic acute kidney injury: personalizing antibiotic dosing through understanding acute kidney injury risk factors and biomarker profilesK23DK119463 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI FITZGERALD, JULIE C. HOLLOWS · 2020 to 2024
$810kNIDDK NIH HHS K23 DK119463NIGMS NIH HHS R35 GM126943
Abstract
PubMed holds no abstract for this paper.
Indexed as
Acute Kidney InjuryBiomarkersChildChild, PreschoolFemaleHumansInfantMaleModels, StatisticalProspective StudiesRecovery of FunctionRisk AssessmentSeverity of Illness IndexShock, SepticBiomarkersacute kidney injuryprecision medicinesepsisseptic shock
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.